Blake Tamara L, Chang Anne B, Marchant Julie M, McElrea Margaret S
Centre for Children's Health Research, Queensland University of Technology, Brisbane, Queensland, Australia.
Indigenous Respiratory Outreach Care Program, The Prince Charles Hospital, Brisbane, Queensland, Australia.
J Paediatr Child Health. 2020 Jul;56(7):1066-1071. doi: 10.1111/jpc.14817. Epub 2020 Feb 24.
National data report respiratory illness to be the most common chronic illness in Australian Indigenous people aged <35 years but multi-centre data on specific diseases is sparse. Respiratory health is now known to be an independent predictor of future all-cause mortality and cardiovascular disease. We aimed to describe the respiratory health profile (clinical and spirometry data) of randomly recruited Indigenous Australian children and young adults from several sites.
As part of the Indigenous Respiratory Reference Values study, 1278 Australian Indigenous children and young adults (aged 3-25 years) were recruited from nine communities (Queensland, n = 8; Northern Territory, n = 1). Self-reported and medical records were used to ascertain respiratory history. Participants were classified as 'healthy' if there was no current/previous respiratory disease history. Spirometry was performed on all participants and assessed according to forced expiratory volume at 1 s impairment.
Medical history data were available for 1245 (97.4%) and spirometry for 1106 participants (86.5%). Asthma and bronchitis were the most commonly reported respiratory conditions (city/regional 19.5% and rural/remote 16.8%, respectively). Participants with a history of any respiratory disease or those living in rural/remote communities had lower lung function compared to the 'healthy' group. Almost 52.0% of the entire cohort had mild-moderate forced expiratory volume at 1 s impairment (47.7% in 'healthy' group, 58.5% in 'respiratory history' group).
The high prevalence of poor respiratory health among Indigenous Australian children/young adults places them at increased risk of future all-cause mortality and cardiovascular disease. Respiratory assessments including spirometry should be part of the routine evaluation of Indigenous Australians.
国家数据报告显示，呼吸系统疾病是澳大利亚35岁以下原住民中最常见的慢性病，但关于特定疾病的多中心数据却很稀少。现在已知呼吸健康是未来全因死亡率和心血管疾病的独立预测因素。我们旨在描述从多个地点随机招募的澳大利亚原住民儿童和年轻人的呼吸健康状况（临床和肺功能数据）。
作为原住民呼吸参考值研究的一部分，从9个社区（昆士兰州，n = 8；北领地，n = 1）招募了1278名澳大利亚原住民儿童和年轻人（年龄3 - 25岁）。通过自我报告和医疗记录来确定呼吸病史。如果没有当前/既往呼吸系统疾病史，参与者被归类为“健康”。对所有参与者进行肺功能测试，并根据1秒用力呼气量损伤情况进行评估。
1245名参与者（97.4%）有病史数据，1106名参与者（86.5%）有肺功能测试数据。哮喘和支气管炎是最常报告的呼吸疾病（城市/地区分别为19.5%，农村/偏远地区分别为16.8%）。与“健康”组相比，有任何呼吸疾病史的参与者或生活在农村/偏远社区的参与者肺功能较低。几乎52.0%的整个队列有轻度 - 中度1秒用力呼气量损伤（“健康”组为47.7%，“有呼吸病史”组为58.5%）。
澳大利亚原住民儿童/年轻人中呼吸健康状况不佳的高患病率使他们面临未来全因死亡率和心血管疾病风险增加。包括肺功能测试在内的呼吸评估应成为澳大利亚原住民常规评估的一部分。
