Clay S A, Ramseyer J C, Fishman L S, Sedgwick R P
Arch Neurol. 1977 Apr;34(4):236-43. doi: 10.1001/archneur.1977.00500160050009.
Eight infants with an acute reversible motor unit disorder are described, including two infants from whom Clostridum botulinum type A was isolated from stool specimens. The clinical spectrum includes constipation, cranial nerve deficits, pupillary involvement, and generalized hypotonic weakness. There were no deaths, and all infants have had complete clinical recovery. A characteristic electromyographic (EMG) pattern was present in part until clinical recovery. This distinctive pattern consisted of brief, small, abundant for power exerted motor unit potentials. This EMG pattern in the context of the clinical syndrome may well be diagnostic for acute infantile motor unit disorder.
本文描述了8例患有急性可逆性运动单位疾病的婴儿，其中2例婴儿的粪便标本中分离出了A型肉毒杆菌。临床症状包括便秘、颅神经功能缺损、瞳孔受累以及全身性低张性肌无力。无一例死亡，所有婴儿均已完全临床康复。部分婴儿在临床康复前出现了特征性的肌电图（EMG）模式。这种独特的模式由短暂、微小、用力时丰富的运动单位电位组成。在这种临床综合征背景下的这种肌电图模式很可能对急性婴儿运动单位疾病具有诊断意义。
