2024年，英国，花生酱被确认为一例婴儿肉毒中毒病例的感染源。

Peanut butter confirmed as the source in a case of infant botulism, United Kingdom, 2024.

作者信息

Crane Rosie J, Amar Corinne Fl, Omoruyi Humphrey, Ahmed Burhan, Finch Jonathan, Kendrick Rachael, Ladhani Shamez, Painset Anais, Rajendram Dunstan, Raphaely Nika, Dwarakanathan Buvana, Guruprasad Suba, Zuhur-Adi Hani, Wong Vanessa K, Godbole Gauri

机构信息

St George's University Hospitals NHS Foundation Trust, London, United Kingdom.

United Kingdom Health Security Agency (UKHSA), London, United Kingdom.

出版信息

Euro Surveill. 2025 Jul;30(30). doi: 10.2807/1560-7917.ES.2025.30.30.2500512.

DOI:10.2807/1560-7917.ES.2025.30.30.2500512

PMID:40747570

Abstract

A 6-month-old infant was hospitalised with suspected infant botulism after being given peanut butter to reduce their risk of developing peanut allergy. type A was detected in their faeces and the peanut butter by PCR and culture. Whole genome sequencing confirmed identical strains, identifying the peanut butter as the source of infection. The infant was treated with human-derived antitoxin Botulism Immune Globulin Intravenous (Human) (BIG-IV) and recovered well. This case highlights potential botulism risk with early peanut introduction.

摘要

一名6个月大的婴儿在食用花生酱以降低患花生过敏风险后，因疑似婴儿肉毒中毒而住院。通过聚合酶链反应（PCR）和培养在其粪便和花生酱中检测出A型肉毒杆菌。全基因组测序证实菌株相同，确定花生酱为感染源。该婴儿接受了人源抗毒素静脉注射用肉毒中毒免疫球蛋白（人）（BIG-IV）治疗，恢复良好。该病例凸显了过早引入花生存在的潜在肉毒中毒风险。