相关水貂的肾多囊病

Polycystic disease of the kidney in related mink.

作者信息

Henriksen P

机构信息

National Veterinary Laboratory, Aarhus, N. Denmark.

出版信息

J Comp Pathol. 1988 Jul;99(1):101-4. doi: 10.1016/0021-9975(88)90109-0.

DOI:10.1016/0021-9975(88)90109-0

PMID:3209755

Abstract

Polycystic kidneys in young related mink kits were seen on a mink farm in 1983 (4 kits) and 1984 (6 kits). The kits showed retarded growth and locomotor abnormalities leading to death in the 1983 kits at the age of 4 months. The renal cysts involved the collecting tubules; there was vacuolization and focal hyperplasia of the epithelium. Other organs were normal. The data available for the condition in mink are insufficient as yet to explain the mode of inheritance.

摘要

1983年（4只）和1984年（6只），在一个水貂养殖场发现幼年水貂幼崽患有多囊肾。这些幼崽生长发育迟缓，有运动异常，1983年的幼崽在4个月大时死亡。肾囊肿累及集合小管；上皮细胞有空泡化和局灶性增生。其他器官正常。关于水貂这种病症的现有数据尚不足以解释其遗传方式。