Department of Biomedical Sciences, University of Sassari, Viale San Pietro 43/b, 07100 Sassari, Italy.
Institute for Genetic and Biomedical Research, National Research Council, traversa La Crucca 3, 07100 Sassari, Italy.
Nutrients. 2020 Feb 21;12(2):566. doi: 10.3390/nu12020566.
At present, specialized companies offering genetic testing services without the involvement of clinicians are growing; this development is a direct consequence of the significant decrease in genotyping and sequencing costs. Online companies offer predictions about the risk of developing complex diseases during one's life course, and they offer suggestions for personal lifestyle. Several companies have been created that provide nutrigenetics services; these companies suggest dietary indications-a central issue in the prevention and etiopathogenesis of specific diseases-based on one's personal genetic background. Dietary patterns are defined on the basis of a limited set of genetic markers. In this article, we analyze the online nutrigenetics services offered by 45 companies worldwide, to obtain an overall picture of the costs, the types of nutritional traits considered and the level of scientific precision of the services proposed. Our analysis clearly highlights the need for specific guidelines, in order to ensure a set of minimum quality standards for the nutrigenetics services offered to the customer.
目前，专门提供遗传检测服务而无需临床医生参与的公司正在不断增加；这种发展是基因分型和测序成本显著降低的直接结果。在线公司提供有关在一个人生命过程中患复杂疾病风险的预测，并为个人生活方式提供建议。已经创建了几家提供营养遗传学服务的公司；这些公司根据个人的遗传背景，为特定疾病的预防和病因学提供饮食建议——这是一个核心问题。饮食模式是基于有限的遗传标记来定义的。在本文中，我们分析了全球 45 家公司提供的在线营养遗传学服务，以全面了解服务的成本、所考虑的营养特征类型以及所提出服务的科学精度水平。我们的分析清楚地突出了需要制定具体的指导方针，以确保为向客户提供的营养遗传学服务设定一套最低质量标准。
