Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea.
Biomedical Research Institute, Pusan National University Hospital, Busan, Korea.
Korean J Gastroenterol. 2020 Feb 25;75(2):94-97. doi: 10.4166/kjg.2020.75.2.94.
Duodenal leiomyosarcoma is a rare condition with a poor prognosis. Early diagnosis of duodenal leiomyosarcoma is challenging because it presents with nonspecific symptoms and endoscopic biopsies usually do not enable a definitive diagnosis. Duodenal leiomyosarcomas are diagnosed on the basis of the histopathological identification of a mesenchymal lesion composed of malignant tumor cells that on immunohistochemical examination is positive for smooth muscle actin and desmin. We report the case of a 38-year-old man who presented with gastrointestinal bleeding and obstruction who was diagnosed with duodenal leiomyosarcoma after surgical resection.
十二指肠平滑肌肉瘤是一种罕见的疾病，预后不良。十二指肠平滑肌肉瘤的早期诊断具有挑战性，因为其表现为非特异性症状，内镜活检通常不能明确诊断。十二指肠平滑肌肉瘤的诊断基于组织病理学识别由恶性肿瘤细胞组成的间叶性病变，免疫组化检查显示平滑肌肌动蛋白和结蛋白阳性。我们报告了 1 例 38 岁男性患者，因胃肠道出血和梗阻就诊，手术后诊断为十二指肠平滑肌肉瘤。
