Dudhe Sakshi S, Mishra Gaurav V, Parihar Pratapsingh, Nimodia Devyansh, Kumari Anjali, Shinde Dhananjay
Radiodiagnosis, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Cureus. 2024 Jul 23;16(7):e65182. doi: 10.7759/cureus.65182. eCollection 2024 Jul.
Leiomyosarcoma (LMS) is an extremely rare malignant pathology affecting smooth muscle cells, with the uterus being the predominant location of LMS. Its occurrence in the duodenum is rare, making it a diagnostic challenge for radiologists. Patients with duodenal LMS can present with very vague symptoms such as abdominal discomfort, loss of weight, or manifestations associated with internal gastrointestinal bleeding. In this case report, we have an 82-year-old female presenting with duodenal LMS, which is a very atypical location. An esophagogastroduodenoscopy and further workup revealed a duodenal mass, which was biopsied. The lump was identified as an LMS using immunohistochemistry and histopathology. Despite its rarity, it presents diagnostic and therapeutic challenges due to its nonspecific clinical manifestations and radiological findings. By exploring the existing literature and clinical insights, we aim to provide a comprehensive understanding of this rare condition, highlighting the need for interdisciplinary collaboration and tailored therapeutic strategies to diagnose and manage this disease entity effectively.
平滑肌肉瘤（LMS）是一种极为罕见的影响平滑肌细胞的恶性病变，子宫是LMS的主要发病部位。其在十二指肠的发生较为罕见，这给放射科医生带来了诊断挑战。十二指肠LMS患者可能出现非常模糊的症状，如腹部不适、体重减轻或与胃肠道内出血相关的表现。在本病例报告中，我们有一位82岁的女性患有十二指肠LMS，这是一个非常不典型的发病部位。经食管胃十二指肠镜检查及进一步检查发现十二指肠有肿物，并进行了活检。通过免疫组织化学和组织病理学检查，该肿块被确定为LMS。尽管其罕见，但由于其非特异性的临床表现和影像学表现，在诊断和治疗方面仍面临挑战。通过查阅现有文献并结合临床见解，我们旨在全面了解这种罕见疾病，强调跨学科协作以及制定针对性治疗策略以有效诊断和管理该疾病实体的必要性。
