Arora Navneet, Shukla Shubham, Vijaykumar Deeksha, Suri Vikas, Kumar Rajender, Pannu Ashok K
Senior Resident, Department of Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Resident, Department of Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Trop Doct. 2020 Jul;50(3):275-277. doi: 10.1177/0049475520908725. Epub 2020 Feb 25.
Histoplasmosis is usually clinically suspected only in people who reside in, are migrants from or are travelling to endemic areas such as North America. Immunocompetent patients with a low level of exposure typically have either subclinical or mild and self-limiting infection. The most common risk for the development of progressive disseminated form is HIV infection. We recently managed two patients with disseminated histoplasmosis, presenting with prolonged fever, significant weight loss, pallor and hepatosplenomegaly. Both were HIV-negative and lived in Himachal Pradesh (India), a region that was considered "-free" until recently.
