辅助性局部抗生素羟基磷灰石生物复合材料在开放性 Gustilo Anderson IIIB 型骨折治疗中的应用
Adjuvant Local Antibiotic Hydroxyapatite Bio-Composite in the management of open Gustilo Anderson IIIB fractures. .
作者信息
Aljawadi Ahmed, Islam Amirul, Jahangir Noman, Niazi Noman, Ferguson Zak, Sephton Benjamin, Elmajee Mohammed, Reid Adam, Wong Jason, Pillai Anand
机构信息
Trauma and Orthopaedics, Manchester Foundation Trust, Southmoor Rd, Wythenshawe, Manchester, M23 9LT, UK.
ST4 Spine Department, Royal Orthopaedic Hospital NHS Foundation Trust, Birmingham, B31 2AP, UK.
出版信息
J Orthop. 2020 Jan 11;18:261-266. doi: 10.1016/j.jor.2020.01.012. eCollection 2020 Mar-Apr.
Abstract
BACKGROUND
This study aims to evaluate outcomes of using Adjuvant Local Antibiotic Hydroxyapatite Bio-Composite in management of Open Gustilo-Anderson IIIB Fractures.
METHODS AND RESULTS
80 patients were managed with single-stage "Fix and Flap" along with intra-operative Adjuvant Local Antibiotic Bio-Composite. Successful fracture union was achieved in 96.1% of patients, with a limb salvage rate of 96.25%. Infection rate was only 1.25%.
CONCLUSION
High union rate and very low deep infection rate can be predictably achieved in complex Open Gustilo-Anderson IIIB fractures by meticulous technique, use of local adjunctive antibiotics bio-composite and a combined ortho-plastic approach.
摘要
背景
本研究旨在评估辅助性局部抗生素羟基磷灰石生物复合材料在开放性 Gustilo-Anderson IIIB 型骨折治疗中的效果。
方法与结果
80 例患者接受了一期“固定与皮瓣”手术，并术中使用辅助性局部抗生素生物复合材料。96.1%的患者实现了骨折成功愈合，保肢率为 96.25%。感染率仅为 1.25%。
结论
通过精细的技术、使用局部辅助抗生素生物复合材料以及联合骨科 - 整形方法，在复杂的开放性 Gustilo-Anderson IIIB 型骨折中可以预期获得高愈合率和极低的深部感染率。
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