Shirodaria P V, Matthews R S
Br J Dermatol. 1977 Jan;96(1):29-34. doi: 10.1111/j.1365-2133.1977.tb05182.x.
A survey of the incidence of molluscum contagiosum virion antigens in patients with single or multiple lesions showed that all lesions contain virus antigen. The virion antigens were detected in the prickle cell, granular and keratin layers. Hyperimmune sera against vaccinia, rabbit-pox and mouse-pox failed to stain the inclusion bodies in molluscum contagiosum lesions. Virus-specific antibodies were present in 69% of the patients. Although virus-specific IgG antibody was predominant, virus-specific IgM and virus-specific IgA were found in a few patients. An IgM staining in the prickle cell, granular and keratin layers of normal skin adjoining the molluscum contagiosum lesion was observed. The virus-specific antibody response was induced in a few patients after the treatment.
一项针对患有单个或多个传染性软疣皮损患者的传染性软疣病毒粒子抗原发生率的调查显示，所有皮损均含有病毒抗原。在棘细胞层、颗粒层和角质层中检测到病毒粒子抗原。抗牛痘、兔痘和鼠痘的超免疫血清未能使传染性软疣皮损中的包涵体染色。69%的患者体内存在病毒特异性抗体。虽然病毒特异性IgG抗体占主导，但在少数患者中也发现了病毒特异性IgM和病毒特异性IgA。在毗邻传染性软疣皮损的正常皮肤的棘细胞层、颗粒层和角质层中观察到IgM染色。少数患者在治疗后诱导出了病毒特异性抗体反应。
