Kumar Sanjeev, Jain Vijay Kumar, Prabhakar Rahul
Department of Orthopedics, PGIMER, Dr. Ram Manohar Lohia Hospital, New Delhi, 110001, India.
J Clin Orthop Trauma. 2020 Mar-Apr;11(2):321-323. doi: 10.1016/j.jcot.2019.06.009. Epub 2019 Jun 11.
Melorheostosis is a rare chronic bone disease, etiology of which remains unclear. It mostly affects lower limbs and clinical features vary in each case. Radiographs show characteristic "candle wax pattern" of hyperostosis. Herein we report four cases of upper limb affection with their symptoms, radiographic findings and treatment. First case presented with gradually progressive swelling in forearm which was initially misdiagnosed as filariasis. Plain radiograph eventually demonstrated melorheostosis of ulna. Second patient had deformity of index finger and pain in hand which was diagnosed on radiograph of hand. Third case presented with progressive flexion deformity of ring and little finger. Fourth patient had ulnar involvement which was an incidental diagnosis. First three patients were managed with bisphosphonates following which there was significant improvement in pain and fourth case was kept on follow-up as he was asymptomatic.
肢骨纹状肥大是一种罕见的慢性骨病，其病因尚不清楚。它主要影响下肢，且每个病例的临床特征各不相同。X线片显示特征性的骨增生“蜡泪样”表现。在此我们报告4例上肢受累病例，包括其症状、影像学表现及治疗情况。首例患者前臂逐渐进行性肿胀，最初被误诊为丝虫病。X线平片最终显示尺骨肢骨纹状肥大。第二例患者示指畸形且手部疼痛，手部X线片确诊。第三例患者环指和小指出现进行性屈曲畸形。第四例患者尺骨受累，为偶然诊断。前三例患者接受双膦酸盐治疗，之后疼痛明显改善，第四例患者因无症状而进行随访。
