Kawabata H, Tsuyuguchi Y, Kawai H, Yasui N
J Hand Surg Am. 1984 Nov;9(6):871-6. doi: 10.1016/s0363-5023(84)80070-2.
The etiology, diagnosis, and treatment of two cases of melorheostosis are reported. The hyperostotic lesion corresponded well with both C7 and C8 segments of a sclerotome. The accompanying subcutaneous tumors in case 1 originated from the medical cutaneous nerve of the forearm, whose axons were coming mainly from the C8 dorsal root ganglion. These findings strongly suggest that the primary disorder exists in sensory nerves. Pain originating from the hyperostosis could be suppressed by the disodium salt of (1-hydroxyethylidene) diphosphonic acid.
报告了两例肢骨纹状肥大症的病因、诊断及治疗情况。骨肥厚性病变与一个体节的C7和C8节段高度吻合。病例1中伴发的皮下肿瘤起源于前臂内侧皮神经，其轴突主要来自C8背根神经节。这些发现强烈提示原发性病变存在于感觉神经中。由骨肥厚引起的疼痛可通过（1-羟基亚乙基）二膦酸二钠盐得到缓解。
