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接受抗凝治疗的静脉血栓栓塞症患者的血小板计数与出血情况：来自RIETE注册研究的经验教训

Platelet Count and Bleeding in Patients Receiving Anticoagulant Therapy for Venous Thromboembolism: Lesson from the RIETE Registry.

作者信息

Di Micco Pierpaolo, Monreal Manuel

机构信息

Department of Internal Medicine and Emergency Room, Ospedale Buon Consiglio Fatebenefratelli, Naples, Italy.

Department of Internal Medicine, Hospital Universitari Germans Trias i Pujol, Universidad Autónoma de Barcelona, Badalona, Barcelona, Spain.

出版信息

J Blood Med. 2019 Dec 31;10:453-456. doi: 10.2147/JBM.S234053. eCollection 2019.

DOI:10.2147/JBM.S234053
PMID:32099496
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6997195/
Abstract

Major bleeding is one of the most dangerous complications for patients undergoing anticoagulant treatment for VTE. Several clinical scores have been planned to identify patients at higher risk of bleeding, and most of them take into consideration the number of platelets in particular if lower than normal. Here we report the clinical experience made with the RIETE registry concerning anticoagulant treatment in the presence of different values of platelets and their related risk of bleeding.

摘要

大出血是接受静脉血栓栓塞症（VTE）抗凝治疗患者最危险的并发症之一。已制定了几种临床评分方法来识别出血风险较高的患者，其中大多数方法特别考虑血小板数量，尤其是低于正常水平时。在此，我们报告RIETE注册研究在不同血小板值情况下进行抗凝治疗及其相关出血风险方面的临床经验。

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Fatal pulmonary embolism or bleeding in patients with venous thromboembolism: implications of real-life data.静脉血栓栓塞患者的致命性肺栓塞或出血：真实数据的影响。
Thromb Res. 2019 Sep;181 Suppl 1:S6-S9. doi: 10.1016/S0049-3848(19)30358-5.
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Safety, effectiveness, and health care cost comparisons among elderly patients with venous thromboembolism prescribed warfarin or apixaban in the United States Medicare population.在美国 Medicare 人群中，接受华法林或阿哌沙班治疗的老年静脉血栓栓塞症患者的安全性、有效性和医疗保健成本比较。
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Net Clinical Benefit of Non-vitamin K Antagonist Oral Anticoagulants for Venous Thromboembolism Prophylaxis in Patients With Cancer: A Systematic Review and Trade-Off Analysis From 9 Randomized Controlled Trials.非维生素K拮抗剂口服抗凝剂用于癌症患者静脉血栓栓塞预防的净临床获益：一项基于9项随机对照试验的系统评价与权衡分析
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Int J Cardiol. 2016 Aug 15;217:85-91. doi: 10.1016/j.ijcard.2016.04.173. Epub 2016 May 3.
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