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作为益生菌的物种:潜力与挑战。

species as probiotics: potentials and challenges.

作者信息

Guo Pingting, Zhang Ke, Ma Xi, He Pingli

机构信息

State Key Laboratory of Animal Nutrition, China Agricultural University, No. 2 Yuanmingyuan West Road, Beijing, 100193 China.

出版信息

J Anim Sci Biotechnol. 2020 Feb 20;11:24. doi: 10.1186/s40104-019-0402-1. eCollection 2020.

Abstract

species, as a predominant cluster of commensal bacteria in our gut, exert lots of salutary effects on our intestinal homeostasis. Up to now, species have been reported to attenuate inflammation and allergic diseases effectively owing to their distinctive biological activities. Their cellular components and metabolites, like butyrate, secondary bile acids and indolepropionic acid, play a probiotic role primarily through energizing intestinal epithelial cells, strengthening intestinal barrier and interacting with immune system. In turn, our diets and physical state of body can shape unique pattern of species in gut. In view of their salutary performances, species have a huge potential as probiotics. However, there are still some nonnegligible risks and challenges in approaching application of them. Given this, this review summarized the researches involved in benefits and potential risks of species to our health, in order to develop species as novel probiotics for human health and animal production.

摘要

[具体物种名称]作为我们肠道中主要的共生细菌群,对我们的肠道稳态发挥着许多有益作用。到目前为止,[具体物种名称]因其独特的生物活性已被报道能有效减轻炎症和过敏性疾病。它们的细胞成分和代谢产物,如丁酸、次级胆汁酸和吲哚丙酸,主要通过为肠道上皮细胞提供能量、加强肠道屏障以及与免疫系统相互作用来发挥益生菌作用。反过来,我们的饮食和身体状态可以塑造肠道中[具体物种名称]的独特模式。鉴于它们的有益表现,[具体物种名称]作为益生菌具有巨大潜力。然而,在将它们应用于实际时仍存在一些不可忽视的风险和挑战。鉴于此,本综述总结了关于[具体物种名称]对我们健康的益处和潜在风险的研究,以便将[具体物种名称]开发为用于人类健康和动物生产的新型益生菌。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9fe7/7031906/fd381895098a/40104_2019_402_Fig1_HTML.jpg

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