Mejía-Zuluaga Mateo, Lacouture Jorge Andrés, Gaviria Maria Clara, Garcés Maria Adelaida, Mejía Ana María, Herrera Sebastián
Resident of Internal Medicine, CES University, Medellín, Colombia.
Resident of Dermatology, CES University, Medellín, Colombia.
Case Rep Rheumatol. 2020 Feb 12;2020:9146842. doi: 10.1155/2020/9146842. eCollection 2020.
Multiple myeloma can have different clinical manifestations, and not all patients present with classic CRAB component. We describe a 46-year-old woman admitted to our hospital with a complaint of a bluish-to-black discoloration of the second toe that was rapidly progressive and acute kidney injury. We documented a Kappa light chain monoclonal gammopathy, increased presence of plasmacytes in bone marrow aspiration, and multiple lytic bone lesions, which led to a diagnosis of multiple myeloma. Although multiple myeloma presenting with blue finger syndrome is uncommon, it must always be considered as a differential diagnosis with this clinical finding.
多发性骨髓瘤可表现出不同的临床表现，并非所有患者都具有典型的CRAB症状。我们报告一例46岁女性患者，因第二趾出现迅速进展的蓝黑色变色及急性肾损伤入院。我们记录到κ轻链单克隆丙种球蛋白病、骨髓穿刺中浆细胞增多以及多处溶骨性骨病变，这些表现最终确诊为多发性骨髓瘤。尽管以蓝指综合征表现的多发性骨髓瘤并不常见，但出现此临床症状时必须始终将其列为鉴别诊断之一。
