Johnson P E, Stuart M A, Hunt J R, Mullen L, Starks T L
United States Department of Agriculture, Grand Forks Human Nutrition Research Center, ND 58202.
J Nutr. 1988 Dec;118(12):1522-8. doi: 10.1093/jn/118.12.1522.
Absorption of stable 65Cu incorporated intrinsically or extrinsically into foods was studied in women fed a diet marginal in Cu content. Isotopic enrichment was 73.1 +/- 1.0 atom percent 65Cu in goose breast meat, 74.9 +/- 0.5 atom percent in goose liver, and 55-69.5 atom percent in two crops of peanuts. Seven women were fed a basal diet containing 1.25 mg Cu/d. At 4-wk intervals, they were fed test meals over a 3-d period; each set of meals contained one of the labeled test foods in amounts with similar copper content. Absorption of 65Cu from intrinsically labeled liver was (mean +/- SD) 65 +/- 4%; extrinsic liver, 65 +/- 10%; E/I = 1.00 +/- 0.16. 65Cu absorption from intrinsically labeled goose breast meat was 54 +/- 6%; extrinsic meat, 52 +/- 10%; E/I = 0.97 +/- 0.18. 65Cu absorption from intrinsically labeled peanut butter was 58 +/- 15%; extrinsic peanut butter, 54 +/- 10%; E/I = 0.93 +/- 0.11. 65Cu absorption from extrinsically labeled sunflower butter was 50 +/- 2%. There were no differences in absorption of intrinsic and extrinsic Cu from these foods. Absorption of Cu was significantly higher from goose liver than from goose meat or sunflower butter (P less than 0.05). With a dietary intake of 1.25 +/- 0.20 mg Cu/d, Cu balance, exclusive of surface losses, was essentially zero (0.01 +/- 0.13 mg/d) in the seven subjects.
对摄入铜含量处于边缘水平饮食的女性,研究了内源性或外源性掺入食物中的稳定65Cu的吸收情况。鹅胸肉中65Cu的同位素富集度为73.1±1.0原子百分比,鹅肝中为74.9±0.5原子百分比,两季花生中为55 - 69.5原子百分比。7名女性摄入含1.25mg铜/天的基础饮食。每隔4周,她们在3天内进食测试餐;每组餐食含有一种标记的测试食物,其铜含量相似。内源性标记肝脏中65Cu的吸收率(均值±标准差)为65±4%;外源性肝脏为65±10%;外源性与内源性吸收率之比(E/I)为1.00±0.16。内源性标记鹅胸肉中65Cu的吸收率为54±6%;外源性肉为52±10%;E/I = 0.97±0.18。内源性标记花生酱中65Cu的吸收率为58±15%;外源性花生酱为54±10%;E/I = 0.93±0.11。外源性标记向日葵酱中65Cu的吸收率为50±2%。这些食物中内源性和外源性铜的吸收没有差异。鹅肝中铜的吸收率显著高于鹅肉或向日葵酱(P<0.05)。在饮食摄入量为1.25±0.20mg铜/天时,7名受试者的铜平衡(不包括体表损失)基本为零(0.01±0.13mg/天)。