Department of Dermatology, Venereology and Allergology, Center for Venous Diseases of the Departments of Dermatology and Surgery, Ruhr University of Bochum, Bochum, Germany.
J Dtsch Dermatol Ges. 2020 Mar;18(3):207-213. doi: 10.1111/ddg.14042. Epub 2020 Feb 26.
With increasing age, it is increasingly common for patients to develop both chronic venous insufficiency (CVI) and peripheral artery disease (PAD). While there are special compression bandage systems commercially available for individuals thus affected, appropriate compression stockings have previously not been available. In the present study, we investigated the safety and effectiveness of a type of compression stocking specifically designed for this patient group (VenoTrain angioflow, Bauerfeind Germany, German compression class 1 with high stiffness).
In a prospective case series, we included patients with both CVI (C3-C5 disease according to CEAP classification) and PAD (ankle-brachial index of < 0.9 and > 0.5; absolute ankle systolic pressure of > 60 mmHg). Primary outcome measures consisted of 1) safety in terms of PAD, as determined by measuring acral pressure using acral photoplethysmography (APPG), and 2) effectiveness in terms of CVI symptoms, as assessed by using a suitable questionnaire (VVSymQ).
Fifty patients were evaluated (mean age: 67.1; mean ankle-brachial index: 0.75 ± 0.77). Fifteen patients had stage IIa PAD (according to Fontaine); 15, stage IIb; the remainder, stage I disease. Thirty-one patients had stage C3 CVI (according to CEAP classification); 16 patients, stage C4; and three patients, stage C5 disease. Immediately after donning the medical compression stocking, systolic arterial pressure in the big toe increased significantly (from 83.3 mmHg ± 27.6 mmHg to 90.8 mmHg ± 24.1 mmHg) (p = 0.026). The VVSymQ score dropped significantly from 5.0 ± 4.95 points to 1.4 ± 2.26 points (p < 0.001), thus reflecting an improvement in CVI symptoms.
The compression stocking tested herein is safe for individuals with an ankle brachial index ≥ 0.5. Skin damage was not observed.
随着年龄的增长，患有慢性静脉功能不全（CVI）和外周动脉疾病（PAD）的患者越来越多。虽然市面上有专门为这类患者设计的特殊压缩绷带系统，但之前没有合适的压缩袜可供选择。在本研究中，我们研究了一种专门为这一患者群体设计的压缩袜的安全性和有效性（Bauerfeind 德国的 VenoTrain angioflow，德国压缩分级 1 级，具有较高的硬度）。
前瞻性病例系列研究，纳入同时患有 CVI（CEAP 分类 C3-C5 疾病）和 PAD（踝肱指数 < 0.9 且 > 0.5；绝对踝收缩压 > 60mmHg）的患者。主要观察指标包括 1）使用指端光体积描记法（APPG）测量指端压力，评估 PAD 的安全性，2）使用合适的问卷（VVSymQ）评估 CVI 症状的有效性。
共评估了 50 例患者（平均年龄：67.1 岁；平均踝肱指数：0.75 ± 0.77）。15 例患者患有 Fontaine 分期的 IIa 期 PAD；15 例患者患有 IIb 期 PAD；其余患者患有 I 期疾病。31 例患者患有 CEAP 分类的 C3 CVI；16 例患者患有 C4 期 CVI；3 例患者患有 C5 期 CVI。穿戴上医用压缩袜后，大脚趾的收缩压显著升高（从 83.3 ± 27.6mmHg 升高至 90.8 ± 24.1mmHg）（p = 0.026）。VVSymQ 评分从 5.0 ± 4.95 分显著下降至 1.4 ± 2.26 分（p < 0.001），表明 CVI 症状得到改善。
对于踝肱指数≥0.5 的患者，所测试的压缩袜是安全的。未观察到皮肤损伤。
