复发性孤立性纤维瘤的挽救性碳离子放射治疗：一例报告及文献综述
Salvage carbon ion radiotherapy for recurrent solitary fibrous tumor: A case report and literature review.
作者信息
Murata Kazuma, Endo Kenji, Aihara Takato, Matsuoka Yuji, Nishimura Hirosuke, Suzuki Hidekazu, Sawaji Yasunobu, Yamamoto Kengo, Fukami Shinjiro, Tanigawa Maki, Matsubayashi Jun, Nagao Toshitaka, Imai Reiko
机构信息
Department of Orthopedic Surgery, Tokyo Medical University, Shinjuku, Tokyo, Japan.
Department of Neurosurgery, Tokyo Medical University, Shinjuku, Tokyo, Japan.
出版信息
J Orthop Surg (Hong Kong). 2020 Jan-Apr;28(1):2309499019896099. doi: 10.1177/2309499019896099.
BACKGROUND
Malignant solitary fibrous tumor (MSFT) arising from the spinal cord is extremely rare and poorly understood mesenchymal neoplasms: only a few MSFT in the spinal canal has been described. We describe the clinical course of the patient with MSFT arising from the thoracic spinal cord.
CASE REPORT
We describe the clinical course of the patient and the radiological and pathological findings of the tumor. The tumor had been resected by microscopic posterior approach and video-assisted thoracic surgery, but local recurrence was observed by MRI at 1-year follow-up period. No metastatic lesion was confirmed. Then, carbon ion radiotherapy (CIRT) was administered to the recurrent lesion. Local suppression has been observed for 40 months after irradiation.
CONCLUSION
Dumbbell-shaped MSFT arising from thoracic spinal cord is a highly unusual presentation. CIRT might be effective for treatment of recurrent tumors.
背景
起源于脊髓的恶性孤立性纤维瘤（MSFT）是极其罕见且了解甚少的间叶性肿瘤：仅报道过少数几例椎管内的MSFT。我们描述了一名起源于胸段脊髓的MSFT患者的临床病程。
病例报告
我们描述了该患者的临床病程以及肿瘤的影像学和病理学表现。肿瘤通过显微镜下后路手术和电视辅助胸腔镜手术切除，但在1年随访期的MRI检查中发现局部复发。未确认有转移病灶。随后，对复发病灶进行了碳离子放疗（CIRT）。放疗后40个月观察到局部肿瘤受到抑制。
结论
起源于胸段脊髓的哑铃形MSFT是一种非常罕见的表现形式。CIRT可能对复发性肿瘤的治疗有效。
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