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术前联合使用温热空气强制加热和温热围手术期静脉输液对剖宫产术中产妇体温的影响:一项前瞻性、随机、对照临床试验。

Effects of combined warmed preoperative forced-air and warmed perioperative intravenous fluids on maternal temperature during cesarean section: a prospective, randomized, controlled clinical trial.

机构信息

Department of Anesthesiology, NO.7 Hospital of Ningbo, Ningbo, Zhejiang Province, China.

Department of Anesthesiology, People's Hospital of Zhejiang Provincial (People's Hospital of Hangzhou Medicine College), Hangzhou, Zhejiang Province, China.

出版信息

BMC Anesthesiol. 2020 Feb 26;20(1):48. doi: 10.1186/s12871-020-00970-7.

Abstract

BACKGROUND

Preventing the frequent perioperative hypothermia incidents that occur during elective caesarean deliveries would be beneficial. This trial aimed at evaluating the effect of preoperative forced-air warming alongside perioperative intravenous fluid warming in women undergoing cesarean sections under spinal anesthesia.

METHODS

We randomly allocated 135 women undergoing elective cesarean deliveries to either the intervention group (preoperative forced-air and intravenous fluid warming, n = 69) or the control group (no active warming, n = 66). The primary outcome measure was the core temperature change between groups from baseline to the end of the surgical procedure. Secondary outcomes included thermal comfort scores, the incidences of shivering and hypothermia (< 36 °C), the core temperature on arrival at the post-anesthesia care unit, neonatal axillary temperature at birth, and Apgar scores.

RESULTS

Two-way repeated measures ANOVA revealed significantly different core temperature changes (from the pre-spinal temperature to that at the end of the procedure) between groups (F = 13.022, P < 0.001). The thermal comfort scores were also higher in the intervention group than in the control group (F = 9.847, P = 0.002). The overall incidence of perioperative hypothermia was significantly lower in the intervention group than in the control group (20.6% vs. 51.6%, P < 0.0001).

CONCLUSIONS

Warming preoperative forced-air and perioperative intravenous fluids may prevent maternal hypothermia, reduce maternal shivering, and improve maternal thermal comfort for patients undergoing cesarean sections under spinal anesthesia.

TRIAL REGISTRATION

The study was registered with the Chinese Clinical Trial Registry (registration number: ChiCTR1800019117) on October26, 2018.

摘要

背景

预防择期剖宫产术中频繁发生的围手术期低体温事件将是有益的。本试验旨在评估术前强制空气加热联合椎管内麻醉下剖宫产术围术期静脉内液体加热对产妇的影响。

方法

我们将 135 名择期行剖宫产术的妇女随机分为干预组(术前强制空气和静脉内液体加热,n=69)和对照组(无主动加热,n=66)。主要结局测量指标为两组从基线到手术结束时核心温度的变化。次要结局包括热舒适度评分、寒战和低体温(<36°C)的发生率、到达麻醉后恢复室时的核心温度、新生儿出生时的腋温以及 Apgar 评分。

结果

双向重复测量方差分析显示两组间核心温度变化(从脊髓前温度到手术结束时的温度)有显著差异(F=13.022,P<0.001)。干预组的热舒适度评分也高于对照组(F=9.847,P=0.002)。干预组围手术期低体温的总发生率明显低于对照组(20.6% vs. 51.6%,P<0.0001)。

结论

术前强制空气加热和围术期静脉内液体加热可能预防产妇低体温、减少产妇寒战,并改善椎管内麻醉下剖宫产术产妇的热舒适度。

试验注册

该研究于 2018 年 10 月 26 日在中国临床试验注册中心(注册号:ChiCTR1800019117)注册。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2097/7043061/4a0bb234e835/12871_2020_970_Fig1_HTML.jpg

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