Immagina Biotechnology s.r.l., Via Sommarive 18, Trento, Italy.
Dalton Trans. 2020 Mar 14;49(10):3333-3340. doi: 10.1039/c9dt04605d. Epub 2020 Feb 26.
Integrating graphene as an inorganic nanostructure within a hydrogel matrix enables the creation of a unique hybrid composite combining the peculiar chemical and physical properties of graphene with the high porosity and stability of hydrogels as for example agarose gel. As a consequence, the resulting material forms a double-network system providing advantages deriving from both the components. In this study, we present the synthesis of novel magnetic porous agarose-based graphene oxide microbeads for the adsorption and separation of positively charged aromatic molecules. The hydrogel-based graphene oxide beads revealed an ultrafast adsorption kinetics for positively charged aromatic dyes. We tested this material for the purification of fluorescent-tagged biomolecules. In addition, reduced graphene oxide microbeads were decorated with palladium nanoparticles, showing a high catalytic activity towards the reduction of dyes by sodium borohydride. Our results show that magnetic agarose based graphene microbeads with enhanced physical-chemical properties can be used for several biochemical applications.
将石墨烯作为一种无机纳米结构整合到水凝胶基质中，可以创造出一种独特的混合复合材料，将石墨烯的特殊化学和物理性质与水凝胶的高孔隙率和稳定性结合起来，例如琼脂糖凝胶。因此，所得到的材料形成了双网络系统，提供了两个组成部分的优势。在这项研究中，我们提出了一种新型的磁性多孔琼脂糖基氧化石墨烯微球的合成方法，用于吸附和分离带正电荷的芳香族分子。基于水凝胶的氧化石墨烯珠对带正电荷的芳香族染料表现出超快的吸附动力学。我们测试了这种材料对荧光标记生物分子的纯化。此外，还原氧化石墨烯微球被钯纳米粒子修饰，对硼氢化钠还原染料表现出很高的催化活性。我们的结果表明，具有增强物理化学性质的基于磁性琼脂糖的石墨烯微球可用于多种生化应用。
