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基于 Gabor 小波变换的关键特征提取算法在腰椎间盘退行性变诊断中的应用。

The application of key feature extraction algorithm based on Gabor wavelet transformation in the diagnosis of lumbar intervertebral disc degenerative changes.

机构信息

Department of Pain Treatment, Tangdu Hospital, The Fourth Military Medical University, Xi'an, China.

The 31638 Troops of The Chinese People's Liberation Army, Kunming, China.

出版信息

PLoS One. 2020 Feb 26;15(2):e0227894. doi: 10.1371/journal.pone.0227894. eCollection 2020.

Abstract

OBJECTIVE

Based on the theoretical basis of Gabor wavelet transformation, the application effects of feature extraction algorithm in Magnetic Resonance Imaging (MRI) and the role of feature extraction algorithm in the diagnosis of lumbar vertebra degenerative diseases were explored.

METHOD

The structure of lumbar vertebra and degenerative changes were respectively introduced to clarify the onset mechanism and pathological changes of lumbar vertebra degenerative changes. Most importantly, the theoretical basis of Gabor wavelet transformation and the extraction effect of feature information in lumbar vertebra MRI images were introduced. The differentiation effects of feature information extraction algorithm on annulus fibrosus and nucleus pulposus were analyzed. In this study, the data of lumbar spine MRI was randomly selected from the Wenzhou Lumbar Spine Research Database as research objects. A total of 130 discs were successfully fitted, and 109 images were graded by a doctor after observation, which was compared with the results of the artificial diagnosis. Through the comparison with the results of observation and diagnosis by professional doctors, the accuracy of feature extraction algorithm based on Gabor wavelet transformation in the diagnosis of lumbar vertebra degenerative changes was analyzed.

RESULTS

  1. Compared with the results of the manual diagnosis, the accuracy of the classification method was 88.3%. In addition, the specificity (SPE), accuracy (ACC), and sensitivity (SEN) of the classification method were respectively 89.5%, 92.4%, and 87.6%. 2. The mutual information method and the KLT algorithm were utilized for vertebral body tracking. The maximum mutual information method was more effective in the case of fewer image sequences; however, with the increase of image frames, the accumulation of errors would make the tracking effects of images get worse. Based on the KLT algorithm, the enhanced vertebral boundary information was selected; the soft tissues showed in the obtained images were smooth, the boundary information of vertebral body was enhanced, and the results were more accurate.

CONCLUSION

The feature extraction algorithm based on Gabor wavelet transformation could easily and quickly realize the localization of the lumbar intervertebral disc, and the accuracy of the results was ensured. In addition, from the aspect of vertebral body tracking, the tracking effects based on the KLT algorithm were better and faster than those based on the maximum mutual information method.

摘要

目的

基于 Gabor 小波变换的理论基础,探讨特征提取算法在磁共振成像(MRI)中的应用效果及在腰椎退行性疾病诊断中的作用。

方法

分别介绍腰椎的结构和退行性改变,阐明腰椎退行性改变的发病机制和病理变化。重点介绍 Gabor 小波变换的理论基础及在腰椎 MRI 图像中特征信息的提取效果,分析特征信息提取算法对纤维环和髓核的区分效果。本研究以温州腰椎研究数据库中的腰椎 MRI 数据为研究对象,随机抽取 130 个椎间盘,经观察后由 1 名医生对 109 个图像进行分级,与人工诊断结果进行对比。通过与专业医生观察和诊断结果对比,分析基于 Gabor 小波变换的特征提取算法在腰椎退行性病变诊断中的准确性。

结果

  1. 与人工诊断结果相比,分类方法的准确率为 88.3%。此外,分类方法的特异性(SPE)、准确性(ACC)和灵敏度(SEN)分别为 89.5%、92.4%和 87.6%。2. 采用互信息法和 KLT 算法进行椎体跟踪,在图像序列较少的情况下,最大互信息法效果更优;但随着图像帧数的增加,误差的累积会使图像跟踪效果变差。基于 KLT 算法,选择增强的椎体边界信息,得到的图像中软组织显示平滑,椎体边界信息增强,结果更准确。

结论

基于 Gabor 小波变换的特征提取算法可以方便、快速地实现腰椎间盘的定位,且保证了结果的准确性。另外,从椎体跟踪方面来看,基于 KLT 算法的跟踪效果优于基于最大互信息法的跟踪效果,且更快。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d737/7043753/cba1f95aacc5/pone.0227894.g001.jpg

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