Gagliardi Martin Julian, Guiroy Alfredo, Sícoli Alfredo, Masanés Nicolás Gonzalez, Ciancio Alejandro Morales
Unidad de Patología Espinal, Hospital Español, Mendoza, Argentina.
Oper Neurosurg (Hagerstown). 2020 Sep 15;19(4):E412. doi: 10.1093/ons/opaa024.
Sacral chordomas are infrequent tumors that arise from remnants of the notochord. They are most often found in the sacrum and skull-base.1,2 These lesions rarely metastasize and usually have an indolent and oligosymptomatic clinical course. Chordomas show low sensitivity to standard radiation therapy and chemotherapy. Operative resection with wide resection margins offers the best long-term prognosis, including longer survival and local control.1,3 However, achieving a complete resection with oncological margins may be difficult because of the anatomic complexity of the sacrococcygeal region.4 The main complications of sacral resection include infections, wound closure defects, and anorectal and urogenital dysfunction. The rate of these complications is significantly increased when the tumor involves the S2 level or above. We report the case of a 64-yr-old male who presented with progressive sacrococcygeal pain and a feeling of incomplete evacuation. A heterogeneous, osteolytic lesion was found at the sacrococcygeal region. Full body imaging tests were negative for other lesions. A computed tomography (CT) guided biopsy was made. We usually use the midline approach in case we have to include the needle path in the resection. The pathology confirmed a sacrococcygeal, low-grade chordoma. We decided to perform an en bloc resection. A posterior, partial sacrectomy was planned distal to the S4 level.
骶骨脊索瘤是一种罕见的肿瘤,起源于脊索的残余部分。它们最常发生于骶骨和颅底。这些病变很少发生转移,通常具有惰性且症状较少的临床病程。脊索瘤对标准放疗和化疗敏感性较低。手术切除并保证切缘阴性可提供最佳的长期预后,包括更长的生存期和局部控制。然而,由于骶尾区域的解剖复杂性,实现肿瘤切缘阴性的完全切除可能具有挑战性。骶骨切除的主要并发症包括感染、伤口闭合缺陷以及肛肠和泌尿生殖功能障碍。当肿瘤累及S2水平及以上时,这些并发症的发生率会显著增加。我们报告一例64岁男性患者,其表现为进行性骶尾疼痛及排便不尽感。在骶尾区域发现一个不均匀的溶骨性病变。全身影像学检查未发现其他病变。进行了计算机断层扫描(CT)引导下的活检。如果必须将穿刺路径包含在切除范围内,我们通常采用中线入路。病理证实为骶尾低级别脊索瘤。我们决定进行整块切除。计划在S4水平远端进行后路部分骶骨切除术。