Hisaeda Keiichi, Koshiishi Tomoko, Sasaki Ayuna, Shinozuka Yasunori, Isobe Naoki, Kawai Kazuhiro
Farm Animal Veterinary Nursing, Okayama University of Science, 1-3 Ikoinooka, Imabari, Ehime 794-8555, Japan.
Laboratory of Veterinary Hygiene, Joint Faculty of Veterinary Medicine, Yamaguchi University, 1677-1 Yoshida, Yamaguchi 753-8515, Japan.
J Vet Med Sci. 2020 Apr 9;82(4):457-462. doi: 10.1292/jvms.19-0678. Epub 2020 Feb 26.
We determined the clinical signs and blood ionized calcium (iCa) levels in dairy cows with peracute coliform mastitis (PCM). The clinical scores at the onset of the disease (day 0) and on day 2 and subsequent days were significantly (P<0.01) higher than those of healthy cows. We found a positive correlation (r=0.894, P<0.01) between iCa and total calcium (TCa) concentrations in the blood of healthy cows ; however there was no correlation from day 0 to day 3 in the blood of PCM cows. Multiple regression analysis revealed that the concentration of iCa was correlated with rectal temperature, hematocrit value, platelet count, and albumin level of PCM cows at the onset of disease (r= -0.804, r=0.6576, r=0.6182, r=0.284, P<0.01, respectively). There was no correlation between the TCa concentration and these parameters for PCM cows at day 0. Low blood iCa concentration at day 0 for PCM cows was related to symptoms of septic shock involving hypothermia, activation of the blood coagulation system, and dehydration.
我们测定了患有超急性大肠杆菌性乳腺炎（PCM）的奶牛的临床症状和血液离子钙（iCa）水平。发病时（第0天）以及第2天和随后几天的临床评分显著（P<0.01）高于健康奶牛。我们发现健康奶牛血液中iCa与总钙（TCa）浓度之间存在正相关（r=0.894，P<0.01）；然而，PCM奶牛在发病第0天至第3天血液中二者无相关性。多元回归分析显示，发病时PCM奶牛的iCa浓度与直肠温度、血细胞比容值、血小板计数和白蛋白水平相关（r分别为-0.804、0.6576、0.6182、0.284，P均<0.01）。对于发病第0天的PCM奶牛，TCa浓度与这些参数无相关性。PCM奶牛发病第0天血液中iCa浓度低与包括体温过低、血液凝固系统激活和脱水在内的感染性休克症状有关。
