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[复发性胸腺瘤的治疗]

[Treatment of Recurrent Thymoma].

作者信息

Liu Xianping, Li Xiao, Li Jianfeng

机构信息

Department of Thoracic Surgery, Peking University People's Hospital, Beijing 100044, China.

出版信息

Zhongguo Fei Ai Za Zhi. 2020 Mar 20;23(3):204-210. doi: 10.3779/j.issn.1009-3419.2020.03.11. Epub 2020 Feb 27.

DOI:10.3779/j.issn.1009-3419.2020.03.11
PMID:32102138
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7118328/
Abstract

Thymoma is a potential malignant disease with a recurrence rate of 10% to 30% after complete resection. There is no agreement on the treatment strategy and standard for recurrent thymoma. The treatment methods include reoperation, chemotherapy, radiotherapy, targeted therapy and immunotherapy. In this article, we review the previous literature and summarize the indications, efficacy and prognosis of different treatments for recurrent thymoma, so as to provide some reference for treatment criteria for recurrent thymoma.

摘要

胸腺瘤是一种潜在的恶性疾病,完整切除术后复发率为10%至30%。对于复发性胸腺瘤的治疗策略和标准尚无共识。治疗方法包括再次手术、化疗、放疗、靶向治疗和免疫治疗。在本文中,我们回顾既往文献,总结复发性胸腺瘤不同治疗方法的适应证、疗效及预后,以期为复发性胸腺瘤的治疗标准提供一些参考。

相似文献

1
[Treatment of Recurrent Thymoma].[复发性胸腺瘤的治疗]
Zhongguo Fei Ai Za Zhi. 2020 Mar 20;23(3):204-210. doi: 10.3779/j.issn.1009-3419.2020.03.11. Epub 2020 Feb 27.
2
Radiotherapy and chemotherapy for invasive thymomas: a multicentric retrospective review of 90 cases. The FNCLCC trialists. Fédération Nationale des Centres de Lutte Contre le Cancer.侵袭性胸腺瘤的放疗与化疗:90例多中心回顾性研究。法国国立癌症中心联合会(FNCLCC)试验组
Int J Radiat Oncol Biol Phys. 1995 Jun 15;32(3):651-9. doi: 10.1016/0360-3016(95)00079-e.
3
Management of malignant thymoma.
Radiat Med. 1990 Mar-Apr;8(2):66-9.
4
Thymoma and myasthenia gravis: a clinical study of 1,089 patients from Japan.胸腺瘤与重症肌无力:对1089例日本患者的临床研究
Ann Thorac Surg. 2005 Jan;79(1):219-24. doi: 10.1016/j.athoracsur.2004.06.090.
5
Natural history and treatment of malignant thymoma.恶性胸腺瘤的自然史与治疗
Oncology (Williston Park). 1998 Jul;12(7):1001-5; discussion 1006.
6
Adjuvant therapy in completely resected malignant thymoma.
Cancer Invest. 2003;21(5):815-6. doi: 10.1081/cnv-120023781.
7
Surgical treatment of recurrent thymoma: is it worthwhile?†.复发性胸腺瘤的外科治疗:是否值得?†
Eur J Cardiothorac Surg. 2016 Jan;49(1):327-32. doi: 10.1093/ejcts/ezv086. Epub 2015 Mar 8.
8
Treatment and prognosis of thymoma: a review of 25 cases.
J Surg Oncol. 1982 Aug;20(4):265-8. doi: 10.1002/jso.2930200417.
9
Recurrence of thymoma: clinicopathological features, re-operation, and outcome.胸腺瘤复发:临床病理特征、再次手术及预后
J Surg Oncol. 2001 Nov;78(3):183-8. doi: 10.1002/jso.1146.
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A pilot study of cisplatin and etoposide with and without radiotherapy for advanced malignant thymoma.顺铂和依托泊苷联合或不联合放疗治疗晚期恶性胸腺瘤的初步研究。
Anticancer Res. 2014 Apr;34(4):2023-7.

引用本文的文献

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Predicting the risk category of thymoma with machine learning-based computed tomography radiomics signatures and their between-imaging phase differences.基于机器学习的 CT 影像组学特征及其成像相位差异预测胸腺瘤风险类别。
Sci Rep. 2024 Aug 19;14(1):19215. doi: 10.1038/s41598-024-69735-3.

本文引用的文献

1
Single-arm, multicentre, phase II trial of nivolumab for unresectable or recurrent thymic carcinoma: PRIMER study.单臂、多中心、Ⅱ期临床试验:nivolumab 治疗不可切除或复发性胸腺癌:PRIMER 研究。
Eur J Cancer. 2019 May;113:78-86. doi: 10.1016/j.ejca.2019.03.012. Epub 2019 Apr 13.
2
A Phase II Study of Pemetrexed in Patients with Recurrent Thymoma and Thymic Carcinoma.培美曲塞治疗复发性胸腺瘤和胸腺癌患者的 II 期研究。
J Thorac Oncol. 2018 Dec;13(12):1940-1948. doi: 10.1016/j.jtho.2018.07.094. Epub 2018 Aug 16.
3
A new application for argon beam coagulation: the thymoma patient with pleural recurrence.氩离子束凝固术的一种新应用:胸膜复发的胸腺瘤患者
J Thorac Dis. 2018 May;10(5):E355-E358. doi: 10.21037/jtd.2018.04.114.
4
Pembrolizumab for Patients With Refractory or Relapsed Thymic Epithelial Tumor: An Open-Label Phase II Trial.帕博利珠单抗治疗难治或复发胸腺癌患者的开放性 II 期临床试验。
J Clin Oncol. 2019 Aug 20;37(24):2162-2170. doi: 10.1200/JCO.2017.77.3184. Epub 2018 Jun 15.
5
Precise Diagnosis and Treatment of Thymic Epithelial Tumors Based on Molecular Biomarkers.基于分子生物标志物的胸腺上皮肿瘤的精准诊断与治疗
Crit Rev Oncog. 2017;22(5-6):507-514. doi: 10.1615/CritRevOncog.2017020577.
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Extrapleural pneumonectomy of recurrent thymoma with pleural dissemination.
Respirol Case Rep. 2018 Feb 28;6(4):e00308. doi: 10.1002/rcr2.308. eCollection 2018 May.
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Lancet Oncol. 2018 Mar;19(3):347-355. doi: 10.1016/S1470-2045(18)30062-7. Epub 2018 Jan 26.
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Phase II Study of Everolimus in Patients With Thymoma and Thymic Carcinoma Previously Treated With Cisplatin-Based Chemotherapy.曾接受顺铂为基础化疗的胸腺瘤和胸腺癌患者中依维莫司的 II 期研究。
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Future Oncol. 2017 Nov;13(27):2429-2439. doi: 10.2217/fon-2017-0236. Epub 2017 Nov 10.
10
JLCS medical practice guidelines for thymic tumors: summary of recommendations.JLCS胸腺肿瘤医学实践指南:推荐意见总结
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