Malan F S, Gruss B, Roper N A, Ashburner A J, du Plessis C A
Hoechst Research Farm, Malelane, Republic of South Africa.
J S Afr Vet Assoc. 1988 Dec;59(4):202-3.
While fenbendazole at 15 mg kg-1 either alone or in combination with resorantel reduced the total burden of Libyostrongylus douglassi by more than 98%, levamisole alone at 30 mg kg-1 was only 28% effective, and in combination with resorantel its efficacy was 67%. These results with levamisole do not correspond with the registered rate of efficacy which is given as at least 80% in South Africa. This is apparently the first reported case of anthelmintic resistance in ostriches.
虽然每千克体重15毫克的芬苯达唑单独使用或与雷琐太尔联合使用时，可使道氏利比亚圆线虫的总感染量减少98%以上，但每千克体重30毫克的左旋咪唑单独使用时的有效率仅为28%，与雷琐太尔联合使用时其有效率为67%。左旋咪唑的这些结果与南非登记的至少80%的有效率不符。这显然是鸵鸟体内抗蠕虫药耐药性的首例报道病例。
