Department of Interventional Cardiology and Cardiac Arrhythmias, University Clinical Hospital Military Memorial Medical Academy - Central Veterans' Hospital in Lodz, Medical University of Lodz, Żeromskiego 113, 90-549, Łódź, Poland.
J Interv Card Electrophysiol. 2021 Jan;60(1):109-114. doi: 10.1007/s10840-020-00715-z. Epub 2020 Feb 26.
Eight-millimeter-tip ablation catheters are characterized by poor mapping resolution as they depend on electrode size and spacing. IntellaTip MiFi XP 8-mm (Boston Scientific) catheters offer high mapping resolution due to 3 mini-electrodes (ME) located at the distal tip of the catheter and are dedicated for cavo-tricuspid isthmus (CTI) radiofrequency ablation (RFA). The aim of the study was to evaluate the usefulness, effectiveness and safety of novel IntellaTip MiFi XP catheter for CTI RFA and its ability to localize anatomical structures of the heart.
The study included 10 patients referred for atrial flutter ablation. The 3D mapping system EnSite Velocity was utilized for catheter visualization. The ME signals were used for tricuspid annulus visualization, RF delivery effectiveness assessment defined as ME signal attenuation, and localization of the gaps in the ablation line. The use of ME signals for TV annulus localization resulted in a 13.9 mm (35.5 ± 4.8 mm vs 49.4 ± 7.8 mm; p < 0.01) shorter ablation line in comparison with the potential ablation line designed using standard bipol. The ablation endpoint, bidirectional block, was achieved in all 10 cases (100%) and lasted for at least 15 min after the last RF delivery. The ablation endpoint was reached after 5.1 ± 1.67 RF applications. The total RF time was 220 ± 61 s. Total procedure time was 66 ± 13.5 min, fluoroscopy time 3.92 ± 4.21 min, and total fluoroscopy dose 40.3 ± 56.5 mGy.
In 3 out of 10 cases, there was a need of filling the gap with 1-2 additional applications after the first linear lesion set. No additional RF applications were required at the annular end of the ablation line. The indirect comparison with previously conducted studies using a standard 8-mm ablation catheter shows that the studied catheter has at least the same or even better performance.
The use of the novel IntellaTip MiFi XP may help to avoid unnecessary RF application especially at the annular part of cavo-tricuspid isthmus and enables a purely electrophysiological approach to atrial flutter ablation, as high-resolution ME signals help to understand local electrophysiological phenomena.
由于电极的大小和间距,8 毫米尖端消融导管的映射分辨率较差。IntellaTip MiFi XP 8 毫米(波士顿科学公司)导管由于导管远端尖端的 3 个微型电极(ME)提供了高映射分辨率,专门用于腔静脉三尖瓣峡部(CTI)射频消融(RFA)。本研究的目的是评估新型 IntellaTip MiFi XP 导管用于 CTI RFA 的有用性、有效性和安全性,以及其定位心脏解剖结构的能力。
该研究纳入了 10 例因心房扑动消融而就诊的患者。使用 EnSite Velocity 三维标测系统进行导管可视化。使用 ME 信号进行三尖瓣环可视化,评估 RF 传递效果,定义为 ME 信号衰减,以及定位消融线中的间隙。使用 ME 信号进行 TV 环定位可使消融线缩短 13.9 毫米(35.5 ± 4.8 毫米比 49.4 ± 7.8 毫米;p < 0.01),与使用标准双极设计的潜在消融线相比。在所有 10 例(100%)中均达到了消融终点双向阻滞,且至少在最后一次 RF 传递后 15 分钟内保持阻滞。消融终点在 5.1 ± 1.67 次 RF 应用后达到。总 RF 时间为 220 ± 61 秒。总手术时间为 66 ± 13.5 分钟,透视时间为 3.92 ± 4.21 分钟,总透视剂量为 40.3 ± 56.5 mGy。
在 10 例患者中有 3 例需要在第一次线性消融线建立后再使用 1-2 次额外的消融来填补间隙。在消融线的环形端不需要额外的 RF 应用。与之前使用标准 8 毫米消融导管进行的研究的间接比较表明,研究中使用的导管至少具有相同或甚至更好的性能。
新型 IntellaTip MiFi XP 的使用可以帮助避免不必要的 RF 应用,特别是在腔静脉三尖瓣峡部的环形部分,并能够实现纯电生理方法进行心房扑动消融,因为高分辨率的 ME 信号有助于理解局部电生理现象。