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本文引用的文献

1
Association between prescription opioid misuse and dimensions of suicidality among college students.大学生处方阿片类药物滥用与自杀意念各维度的关系。
Psychiatry Res. 2020 May;287:112469. doi: 10.1016/j.psychres.2019.07.002. Epub 2019 Jul 4.
2
Depression and Anxiety Among Patients on Chronic Opioid Therapy.接受慢性阿片类药物治疗患者中的抑郁和焦虑
Health Serv Res Manag Epidemiol. 2018 Apr 19;5:2333392818771243. doi: 10.1177/2333392818771243. eCollection 2018 Jan-Dec.
3
Sources of Prescription Medication Misuse Among Young Adults in the United States: The Role of Educational Status.美国青年处方药滥用的来源:教育状况的作用。
J Clin Psychiatry. 2018 Mar/Apr;79(2). doi: 10.4088/JCP.17m11958.
4
The Association between Non-Medical Prescription Drug Use and Suicidal Behavior among United States Adolescents.美国青少年非医疗性处方药使用与自杀行为之间的关联。
AIMS Public Health. 2014 Nov 4;1(4):226-240. doi: 10.3934/publichealth.2014.4.226. eCollection 2014.
5
Understanding the demand side of the prescription opioid epidemic: Does the initial source of opioids matter?了解处方阿片类药物流行的需求端:阿片类药物的初始来源重要吗?
Drug Alcohol Depend. 2017 Apr 1;173 Suppl 1:S4-S10. doi: 10.1016/j.drugalcdep.2016.03.014.
6
Perceptions of Harm and Reasons for Misuse of Prescription Opioid Drugs and Reasons for Not Seeking Treatment for Physical or Emotional Pain Among a Sample of College Students.大学生样本中对处方阿片类药物滥用的危害认知、滥用原因以及身体或情感疼痛不寻求治疗的原因
Subst Use Misuse. 2017 Jan 2;52(1):92-99. doi: 10.1080/10826084.2016.1222619. Epub 2016 Sep 28.
7
Prescription Opioid Duration, Dose, and Increased Risk of Depression in 3 Large Patient Populations.3个大型患者群体中处方阿片类药物的使用时长、剂量与抑郁症风险增加
Ann Fam Med. 2016 Jan-Feb;14(1):54-62. doi: 10.1370/afm.1885.
8
Depression from childhood into late adolescence: Influence of gender, development, genetic susceptibility, and peer stress.从童年到青少年晚期的抑郁:性别、发育、遗传易感性和同伴压力的影响。
J Abnorm Psychol. 2015 Nov;124(4):803-16. doi: 10.1037/abn0000089.
9
Opioid-use disorder among patients on long-term opioid therapy: impact of final DSM-5 diagnostic criteria on prevalence and correlates.长期接受阿片类药物治疗患者的阿片类药物使用障碍:《精神疾病诊断与统计手册》第五版最终诊断标准对患病率及相关因素的影响
Subst Abuse Rehabil. 2015 Aug 19;6:83-91. doi: 10.2147/SAR.S85667. eCollection 2015.
10
Screening and case finding for major depressive disorder using the Patient Health Questionnaire (PHQ-9): a meta-analysis.使用患者健康问卷(PHQ-9)筛查和发现重度抑郁症:一项荟萃分析。
Gen Hosp Psychiatry. 2015 Nov-Dec;37(6):567-76. doi: 10.1016/j.genhosppsych.2015.06.012. Epub 2015 Jun 18.

对参与娱乐性滥用处方阿片类药物的美国大学生样本进行抑郁症筛查。

Screening for depression among a sample of US college students who engage in recreational prescription opioid misuse.

作者信息

Davis Robert E, Bass Martha A, Wade M Allison, Nahar Vinayak K

机构信息

Substance Use and Mental Health Laboratory, Department of Health, Human Performance and Recreation, University of Arkansas, 155 N. Stadium Dr. HPER 310B, Fayetteville, AR 72701, USA.

Department of Health, Exercise Science Recreation Management, University of Mississippi, 218 Turner Center, University, MS 38677, USA.

出版信息

Health Promot Perspect. 2020 Jan 28;10(1):59-65. doi: 10.15171/hpp.2020.10. eCollection 2020.

DOI:10.15171/hpp.2020.10
PMID:32104658
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7036209/
Abstract

Among student populations, literature has identified associations between prescription opioid misuse and symptoms of depression such as hopelessness, sadness, and emotional pain. Thus far, existing literature has yet to investigate associations between prescription opioid misuse and depression using validated screening instruments for depression when exploring such associations. The purpose of this study was to utilize a validated screening tool to explore quantifiable presence of depression among college students who engage in recreational prescription opioid misuse (RPOM). Additionally, gender differences in depression and co-occurring substance use are examined. Students (n = 104) of a large university in the Southeastern United States who reported ROM within the past 6 months completed instrumentation assessing demographics, substance use, as well as, screening tools for depression and possible opioid use disorder (OUD). Positive depression screens were significantly higher among females, however, nearly56% of participants screened positive for major depression. Though high levels of co-occurring substance use were observed among the entire sample, males were significantly more likely to report cocaine use, more frequent use of alcohol and marijuana, as well as, exhibit a positive screen for disordered opioid use, at a rate 5 times that of their female counterparts. Students who engage in RPOM are a particularly heightened-risk subsample of the college population who exhibit high levels of depressive symptomatology and substance use behavior. Targeted programming and further investigations are needed among this specific population. Future studies are encouraged to utilize validated instruments when assessing depression among students.

摘要

在学生群体中,已有文献指出处方阿片类药物滥用与抑郁症状之间存在关联,如绝望、悲伤和情感痛苦。到目前为止,在探索此类关联时,现有文献尚未使用经过验证的抑郁症筛查工具来研究处方阿片类药物滥用与抑郁症之间的关联。本研究的目的是利用一种经过验证的筛查工具,探讨在进行娱乐性处方阿片类药物滥用(RPOM)的大学生中抑郁症的可量化存在情况。此外,还研究了抑郁症和并发物质使用方面的性别差异。美国东南部一所大型大学的学生(n = 104)报告在过去6个月内有娱乐性处方阿片类药物滥用行为,他们完成了评估人口统计学、物质使用情况以及抑郁症和可能的阿片类药物使用障碍(OUD)筛查工具的测评。女性中抑郁症筛查呈阳性的比例显著更高,然而,近56%的参与者重度抑郁症筛查呈阳性。尽管在整个样本中观察到并发物质使用水平较高,但男性报告使用可卡因、更频繁使用酒精和大麻以及阿片类药物使用障碍筛查呈阳性的可能性显著更高,是女性的5倍。进行娱乐性处方阿片类药物滥用的学生是大学生群体中一个特别高危的子样本,他们表现出高水平的抑郁症状和物质使用行为。需要针对这一特定人群开展有针对性的项目和进一步调查。鼓励未来的研究在评估学生抑郁症时使用经过验证的工具。