Kaman Ayşe, Tanır Gönül, Çakmakçı Emin, Demir Pervin, Öz Fatma Nur, Teke Türkan Aydın, Metin Özge, Gayretli-Aydın Zeynep Gökçe, Karaman Ayşe
Departments of Pediatric Infectious Diseases, Dr. Sami Ulus Maternity and Children's Training and Research Hospital.
Departments of Radiology, Dr. Sami Ulus Maternity and Children's Training and Research Hospital.
Turk J Pediatr. 2019;61(5):704-713. doi: 10.24953/turkjped.2019.05.009.
Kaman A, Tanır G, Çakmakçı E, Demir P, Öz FN, Aydın Teke T, Metin Ö, Gayretli Aydın ZG, Karaman A. Characteristics, diagnosis, and treatment modality of pediatric patients with cystic echinococcosis: a single centre experience. Turk J Pediatr 2019; 61: 704-713. Cystic echinococcosis (CE) is among the most common zoonotic infections worldwide. Studies about CE are limited in childhood. The aim of this study was to evaluate clinical, radiological and laboratory characteristics of childhood CE at a tertiary care pediatric hospital. Medical records of children with CE were analyzed between January 2005 and January 2015. A total of 130 patients with a median age of 10.4 years (IQR= 7.2-years-13.2 years) were evaluated. The anatomic locations of cysts were as follows; liver (76.9%), lung (36.9%), spleen (6.2%), pelvic region (3.8%) and kidney (2.3%). The most common symptoms were abdominal pain and cough in the patients with liver cysts and lung cysts, respectively. The indirect hemagglutination (IHA) test positivity was 58%. Elevated serum total immunoglobulin E levels were detected in 59% of the patients. Fourty-four patients with liver CE, 33 patients with lung CE were treated surgically and 23 patients with liver CE were treated with percutaneous aspiration, injection and re-aspiration (PAIR) along with medical treatment. The recurrence was observed in five patients with liver CE. It was demonstrated that CE mainly involves liver but lung cysts are more frequently symptomatic and prone to be complicated than liver cysts in children. IHA test positivity together with abdominal ultrasonography are useful to diagnose liver CE but thorax CT is usually needed to diagnose lung CE. Liver cysts that are sized greater than 5 cm are more frequently treated with PAIR or surgery but smaller liver cysts can be treated medically.
卡曼 A、塔尼尔 G、恰克马克奇 E、德米尔 P、厄兹 FN、艾登·特克 T、梅廷 Ö、盖雷特里·艾登 ZG、卡拉曼 A。儿童囊性棘球蚴病患者的特征、诊断及治疗方式：单中心经验。《土耳其儿科学杂志》2019 年；61: 704 - 713。囊性棘球蚴病（CE）是全球最常见的人畜共患感染之一。关于 CE 在儿童期的研究有限。本研究的目的是评估一家三级护理儿科医院中儿童 CE 的临床、放射学和实验室特征。对 2005 年 1 月至 2015 年 1 月期间患有 CE 的儿童的病历进行了分析。共评估了 130 例患者，中位年龄为 10.4 岁（四分位间距 = 7.2 岁 - 13.2 岁）。囊肿的解剖位置如下：肝脏（76.9%）、肺（36.9%）、脾脏（6.2%）、盆腔区域（3.8%）和肾脏（2.3%）。肝脏囊肿和肺囊肿患者最常见的症状分别是腹痛和咳嗽。间接血凝试验（IHA）阳性率为 58%。59%的患者检测到血清总免疫球蛋白 E 水平升高。44 例肝脏 CE 患者、33 例肺 CE 患者接受了手术治疗，23 例肝脏 CE 患者接受了经皮穿刺抽吸、注射和再抽吸（PAIR）并辅以药物治疗。5 例肝脏 CE 患者出现复发。结果表明，CE 在儿童中主要累及肝脏，但肺囊肿比肝脏囊肿更易出现症状且更容易发生并发症。IHA 试验阳性结合腹部超声有助于诊断肝脏 CE，但诊断肺 CE 通常需要胸部 CT。直径大于 5 cm 的肝脏囊肿更常采用 PAIR 或手术治疗，但较小的肝脏囊肿可采用药物治疗。
