Djuricic Slavisa M, Grebeldinger Slobodan, Kafka Dejan I, Djan Igor, Vukadin Miroslav, Vasiljevic Zorica V
Mother and Child Health Institute of Serbia Dr. Vukan Cupic, Belgrade, Serbia.
Parasitol Int. 2010 Jun;59(2):257-61. doi: 10.1016/j.parint.2010.02.011. Epub 2010 Mar 3.
Cystic echinococcosis (CE) is a public health problem in countries having such endemic areas. Epidemiological studies of CE, especially pediatric, are rare. The aim of this study was to evaluate epidemiological and clinical characteristics of CE in children in Serbia. Data were obtained retrospectively from the case records of patients under the age of 18 years admitted for surgical treatment of CE at two large pediatric medical institutions in the period 1990-2006. Patients' age, number of cysts and their anatomic location were evaluated in relation to differences by patients' gender and socio-geographic status (urban or rural origin). The study included 149 children with 272 hydatid cysts. The mean age of patients was 10.1+/-3.8 years. There were no significant differences in the number of patients in relation to gender and urban:rural origin. There were no significant differences in patients' age at the time of surgery or the number of cysts per patient when patients' gender or socio-geographic status was evaluated. The anatomic location of cysts was as follows: liver (N=165; 60.7%), lungs (N=82; 30.1%), and other locations (N=25; 9.2%). Multiple cysts, and combined liver/lung involvement were identified in 34.2% (N=51), and 6.0% (N=9) of patients, respectively. Hepatic cysts were significantly more common in girls than in boys. There were no significant differences in anatomic location of cysts between socio-geographic groups. The large number of infected children during a long period of investigation indicates an active transmission of disease and a lack of program for control and prevention of CE in Serbia.
囊性棘球蚴病（CE）在有此类流行地区的国家是一个公共卫生问题。关于CE的流行病学研究，尤其是儿科方面的研究很少。本研究的目的是评估塞尔维亚儿童CE的流行病学和临床特征。数据是从1990年至2006年期间在两家大型儿科医疗机构接受CE手术治疗的18岁以下患者的病历中回顾性获取的。根据患者的性别和社会地理状况（城市或农村出身）的差异，对患者的年龄、囊肿数量及其解剖位置进行了评估。该研究包括149名患有272个包虫囊肿的儿童。患者的平均年龄为10.1±3.8岁。在患者数量方面，性别和城市与农村出身之间没有显著差异。在评估患者性别或社会地理状况时，手术时患者的年龄或每位患者的囊肿数量没有显著差异。囊肿的解剖位置如下：肝脏（N = 165；60.7%）、肺（N = 82；30.1%）和其他位置（N = 25；9.2%）。分别有34.2%（N = 51）和6.0%（N = 9）的患者发现有多个囊肿以及肝脏/肺联合受累。肝囊肿在女孩中比在男孩中明显更常见。社会地理群体之间囊肿的解剖位置没有显著差异。在长时间的调查中大量受感染儿童表明疾病在塞尔维亚有活跃传播，且缺乏CE控制和预防计划。
