外源性睾酮对跨性别男性生殖的影响。
Impact of Exogenous Testosterone on Reproduction in Transgender Men.
作者信息
Moravek Molly B, Kinnear Hadrian M, George Jenny, Batchelor Jourdin, Shikanov Ariella, Padmanabhan Vasantha, Randolph John F
机构信息
Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, Michigan.
Department of Urology, University of Michigan, Ann Arbor, Michigan.
出版信息
Endocrinology. 2020 Mar 1;161(3). doi: 10.1210/endocr/bqaa014.
Abstract
Studies show that a subset of transgender men desire children; however, there is a paucity of literature on the effect of gender-affirming testosterone therapy on reproductive function. In this manuscript, we will review the process of gender-affirming hormone therapy for transgender men and what is known about ovarian and uterine consequences of testosterone exposure in transgender men; draw parallels with existing animal models of androgen exposure; summarize the existing literature on parenting experiences and desires in transgender people; discuss considerations for assisted reproductive technologies and fertility preservation; and identify gaps in the literature and opportunities for further research.
摘要
研究表明，一部分跨性别男性渴望生育；然而，关于性别肯定性睾酮治疗对生殖功能影响的文献却很少。在本论文中，我们将回顾跨性别男性性别肯定性激素治疗的过程，以及睾酮暴露对跨性别男性卵巢和子宫影响的已知情况；与现有的雄激素暴露动物模型进行对比；总结关于跨性别者育儿经历和愿望的现有文献；讨论辅助生殖技术和生育力保存的注意事项；并找出文献中的空白以及进一步研究的机会。
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