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无晶状体眼大泡性角膜病变的 Descemet 膜内皮角膜移植和人工晶状体植入。

Descemet membrane endothelial keratoplasty and intraocular lens implantation in cases of aphakic bullous keratopathy.

机构信息

Department of Ophthalmology, Adana City Training and Research Hospital, Adana, Turkey.

出版信息

Semin Ophthalmol. 2020 Jan 2;35(1):86-93. doi: 10.1080/08820538.2020.1733031. Epub 2020 Feb 27.

DOI:10.1080/08820538.2020.1733031
PMID:32105503
Abstract

: To present the results of a modified sutured transcleral or sutureless intrascleral three-piece foldable intraocular lens (IOL) implantation with Descemet membrane endothelial keratoplasty (DMEK) in cases of aphakic bullous keratopathy (ABK) with inadequate capsular support.: Twenty-one eyes of 21 patients with ABK and inadequate capsular support who underwent DMEK with three-piece foldable IOL implantation from September 2015 to June 2018 were analyzed, retrospectively. Two techniques were used in IOL implantation; sutureless intrascleral fixation of the IOL (ISF-IOL) and sutured transscleral-fixated IOL (TSF-IOL) implantation.: Rebubblings due to the graft detachment were needed in 9 (43%) of 21 eyes in the early postoperative period. At the last follow-up visit, 18 (85.7%) of DM grafts were attached. Any complication related to IOL implantation was not observed in the ISF-IOL cases. Exposure of the fixation suture in 1 (25%) of 4 TSF-IOL cases was seen, postoperatively. The increase in the mean best-corrected visual acuity (BCVA) at the last follow-up visit was statistically significant when compared to the mean preoperative BCVA ( < .001). The mean preoperative central corneal thickness was decreased from 883.3 ± 111.8 (700-1150) μm to 582.3 ± 118.2 (490-990) μm at the last follow-up visit ( < .001).: DMEK combined with sutureless/sutured three-piece foldable IOL implantation appears to be a feasible method for the management in ABK without adequate capsular support. A faster visual recovery can be obtained with the techniques presented.

摘要

: 介绍在无充分囊袋支持的大泡性角膜病变(ABK)中,联合应用撕囊膜内皮角膜移植(DMEK)和无晶状体眼或有晶状体眼的三段式可折叠人工晶状体(IOL)植入术的结果。

: 回顾性分析了 2015 年 9 月至 2018 年 6 月期间因 ABK 且无充分囊袋支持而接受 DMEK 联合三段式可折叠 IOL 植入术的 21 例(21 只眼)患者的临床资料。IOL 植入采用两种技术:无晶状体眼或有晶状体眼的巩膜内固定(ISF-IOL)和缝线固定巩膜外固定(TSF-IOL)。

: 术后早期 21 只眼中有 9 只(43%)因移植物脱离需要再次复位。最后一次随访时,18 只(85.7%)DM 移植物附着。在 ISF-IOL 病例中未观察到与 IOL 植入相关的任何并发症。在 4 只 TSF-IOL 病例中有 1 只(25%)术后发现固定缝线暴露。与术前平均最佳矫正视力(BCVA)相比,最后一次随访时平均 BCVA 显著增加( < 0.001)。术前中央角膜厚度为 883.3 ± 111.8μm(700-1150μm),最后一次随访时为 582.3 ± 118.2μm(490-990μm)( < 0.001)。

: 对于无充分囊袋支持的 ABK,DMEK 联合无晶状体眼/有晶状体眼的三段式可折叠 IOL 植入术似乎是一种可行的治疗方法。所介绍的技术可以更快地恢复视力。

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引用本文的文献

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Descemet membrane endothelial keratoplasty: Update on preoperative considerations, surgical techniques, and outcomes.Descemet 膜内皮角膜移植术:术前考虑因素、手术技术和结果的更新。
Indian J Ophthalmol. 2022 Sep;70(9):3222-3238. doi: 10.4103/ijo.IJO_2933_21.