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去表皮自动角膜内皮移植术在异常前段中的应用:巩膜压陷技术增强供体贴附。

Descemet's stripping automated endothelial keratoplasty in abnormal anterior segment: scleral indentation technique to enhance donor adherence.

机构信息

Department of Ophthalmology, China Medical University Hospital, No. 2, Yuh Der Road, Taichung, Taiwan.

出版信息

Graefes Arch Clin Exp Ophthalmol. 2013 Jun;251(6):1557-63. doi: 10.1007/s00417-013-2264-0. Epub 2013 Jan 29.

DOI:10.1007/s00417-013-2264-0
PMID:23358656
Abstract

BACKGROUND

To describe a scleral indentation technique to enhance donor adherence in Descemet's stripping and automated endothelial keratoplasty (DSAEK) in patients with abnormal anterior segment.

METHODS

In patients with visual potential, we performed transscleral fixation of a foldable intraocular lens (IOL) and DSAEK. In patients only for pain relief, we performed DSAEK without IOL implantation. During air tamponade, we injected only a medium air bubble instead of big bubble into anterior chamber and used scleral indentation technique as an aid. The position of the grafts was checked by the slit lamp and anterior segment optical coherence tomography (AS-OCT).

RESULTS

Five eyes of five patients of aphakic bullous keratopathy (ABK) or pseudophakic bullous keratopathy (PBK) with anterior chamber IOL (AC IOL) were included in this non-comparative interventional case series. The grafts attached well in all patients without any graft dislocation intraoperatively and during the follow-up period. There was no pupillary block or peripheral anterior synechiae postoperatively.

CONCLUSIONS

Scleral indentation technique with or without transscleral fixation of a foldable IOL in DSAEK can facilitate the air tamponade and enhance the donor adherence in certain anterior segment abnormities.

摘要

背景

描述一种巩膜凹陷技术,以增强在异常前段的患者中进行的撕囊和自动化内皮角膜移植术(DSAEK)中的供体附着。

方法

在有视力潜力的患者中,我们进行了折叠式人工晶状体(IOL)的经巩膜固定和 DSAEK。对于仅为缓解疼痛的患者,我们进行了 DSAEK 而没有植入 IOL。在空气填充期间,我们仅在前房内注入中等气泡而不是大气泡,并使用巩膜凹陷技术作为辅助。通过裂隙灯和前节光学相干断层扫描(AS-OCT)检查移植物的位置。

结果

这项非比较性介入性病例系列研究纳入了五例无晶状体泡状角膜病变(ABK)或人工晶状体后泡状角膜病变(PBK)患者的五眼。在所有患者中,移植物在手术中和随访期间均附着良好,没有任何移植物脱位。术后没有瞳孔阻滞或周边前粘连。

结论

在 DSAEK 中,无论是否进行折叠式 IOL 的经巩膜固定,巩膜凹陷技术都可以促进空气填充,并增强某些前段异常中的供体附着。

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本文引用的文献

1
Descemet's stripping automated endothelial keratoplasty outcomes compared with penetrating keratoplasty from the Cornea Donor Study.Descemet 氏膜撕除自动化内皮角膜移植术与角膜供体研究中的穿透性角膜移植术的结果比较。
Ophthalmology. 2010 Mar;117(3):438-44. doi: 10.1016/j.ophtha.2009.07.036. Epub 2010 Jan 19.
2
Endothelial keratoplasty: the use of viscoelastic as an aid in reattaching the dislocated graft in abnormally structured eyes.内皮角膜移植术:在结构异常的眼中使用粘弹性物质辅助重新固定脱位的移植物。
Ophthalmology. 2009 Oct;116(10):1897-900. doi: 10.1016/j.ophtha.2009.03.049. Epub 2009 Jul 9.
3
A modified technique for descemet membrane stripping automated endothelial keratoplasty to minimize endothelial cell loss.
一种改良的后弹力层剥离自动内皮角膜移植术技术,以尽量减少内皮细胞损失。
Arch Ophthalmol. 2008 Aug;126(8):1133-7. doi: 10.1001/archopht.126.8.1133.
4
Closed-chamber pulling-injection system for donor graft insertion in endothelial keratoplasty.用于内皮角膜移植术中供体移植物植入的密闭腔室牵拉注射系统。
J Cataract Refract Surg. 2008 Mar;34(3):353-6. doi: 10.1016/j.jcrs.2007.11.019.
5
Endothelial cell loss after Descemet's stripping endothelial keratoplasty in a large prospective series.在一项大型前瞻性研究系列中,Descemet膜剥脱内皮角膜移植术后的内皮细胞丢失情况。
Ophthalmology. 2008 Mar;115(3):488-496.e3. doi: 10.1016/j.ophtha.2007.10.035. Epub 2007 Dec 27.
6
Endothelial cell loss after descemet stripping with endothelial keratoplasty influencing factors and 2-year trend.后弹力层剥除内皮角膜移植术后内皮细胞丢失的影响因素及2年趋势
Ophthalmology. 2008 May;115(5):857-65. doi: 10.1016/j.ophtha.2007.06.033. Epub 2007 Sep 14.
7
Single-piece foldable acrylic intraocular lens implantation in the sulcus in eyes with posterior capsule tear during phacoemulsification.超声乳化术中后囊膜破裂的眼中单块可折叠丙烯酸酯人工晶状体沟内植入术
J Cataract Refract Surg. 2005 Aug;31(8):1593-7. doi: 10.1016/j.jcrs.2005.01.029.
8
Transscleral fixation of a foldable intraocular lens in aphakic vitrectomized eyes.
J Cataract Refract Surg. 2003 Dec;29(12):2390-6. doi: 10.1016/s0886-3350(03)00338-9.
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Transscleral fixation of foldable intraocular lens after pars plana lensectomy in eyes with a subluxated lens.晶状体半脱位眼行平坦部晶状体切除术后可折叠人工晶状体的经巩膜固定术
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