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左顶叶缘上回动静脉畸形致放射性坏死的显微外科切除

Microsurgical Resection of a Left Supramarginal Gyrus AVM Causing Radionecrosis.

机构信息

Department of Neurosurgery, Universidade Federal de Sao Paulo, São Paulo-SP, Brazil.

Department of Neurosurgery, Universidade Federal de Sao Paulo, São Paulo-SP, Brazil.

出版信息

World Neurosurg. 2020 Jun;138:317. doi: 10.1016/j.wneu.2020.02.082. Epub 2020 Feb 24.

DOI:10.1016/j.wneu.2020.02.082
PMID:32105879
Abstract

Late radiation necrosis is a rare entity presenting in 2.2% to 9% of radiation-treated arteriovenous malformations (AVMs). It occurs by a mean of 3 years following treatment. There are few reports in the literature of radionecrosis and solid lesions treated with surgery. To the authors' knowledge, this case has the longest interval between radiosurgery and the presentation of cerebral necrosis. In this surgical video, we present the case of a 51-year-old female with a left supramarginal gyrus AVM that received radiosurgery with gamma knife; after 20 years, she began having seizures and aphasia. The magnetic resonance imaging scan revealed a lesion simulating an intra-axial tumor causing important edema and mass effect. Medical treatment was given including high-dose steroids without success, therefore microsurgery was performed. The surgery was presented in a step-by-step basis and correlation was performed with the involved adjacent anatomy, to illustrate the anatomy of the approach and surgical landmarks. The patient's symptoms resolved completely, and the postoperative magnetic resonance imaging scan showed complete resection and resolution of the edema. The histopathological findings were consistent with a radionecrosis and AVM. The patient signed the Institutional Consent Form, which states that she accepts the procedure and allows the use of her images and videos for any type of medical publications in conferences and/or scientific articles.

摘要

迟发性放射性坏死是一种罕见的疾病,在接受放射治疗的动静脉畸形(AVM)中发生率为 2.2%至 9%。它通常在治疗后 3 年发生。文献中仅有少数关于放射性坏死和实性病变采用手术治疗的报道。据作者所知,这是伽玛刀放射外科治疗后发生脑坏死时间间隔最长的病例。在这个手术视频中,我们介绍了一位 51 岁女性的病例,她的左侧缘上回 AVM 接受了伽玛刀放射外科治疗;20 年后,她开始出现癫痫和失语。磁共振成像扫描显示病变模拟脑内肿瘤,导致严重水肿和占位效应。给予包括大剂量类固醇在内的药物治疗,但没有成功,因此进行了显微手术。手术以逐步的方式呈现,并与涉及的相邻解剖结构相关联,以说明手术入路和手术标志的解剖结构。患者的症状完全缓解,术后磁共振成像扫描显示完全切除和水肿消退。组织病理学检查结果与放射性坏死和 AVM 一致。患者签署了机构同意书,同意接受该程序,并允许将其图像和视频用于会议和/或科学文章中的任何类型的医学出版物。

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Microsurgical Resection of a Left Supramarginal Gyrus AVM Causing Radionecrosis.左顶叶缘上回动静脉畸形致放射性坏死的显微外科切除
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引用本文的文献

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Predictive Factors of Radiation-Induced Changes Following Single-Session Gamma Knife Radiosurgery for Arteriovenous Malformations.单次伽玛刀放射外科治疗动静脉畸形后辐射诱导变化的预测因素
J Clin Med. 2021 May 19;10(10):2186. doi: 10.3390/jcm10102186.