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[多发伤患者预防性静脉使用肝素后发生肺栓塞的风险]

[Risk of lung embolism following preventive intravenous use of heparin in polytraumatized patients].

作者信息

Bosch U, Reilmann H, Sturm J, Kleemann W J, Windus G

机构信息

Unfallchirurgische Klinik, Medizinische Hochschule Hannover.

出版信息

Langenbecks Arch Chir. 1988;373(4):214-6. doi: 10.1007/BF01261811.

DOI:10.1007/BF01261811
PMID:3210844
Abstract

The risk of thrombo-embolic complications in multiple injured patients is increased due to several pathophysiological factors. The purpose of this study was to analyse the effect of a continuous IV heparin prophylaxis (10000IE/24h) in polytraumatized patients. A post-mortem evaluation of 72 decreased patients out of 373 multiple trauma patients treated during 1984-1985 was performed. In one patient multiple major pulmonary emboli were found to contribute to his death. No deep vein thrombosis as well as no fulminant pulmonary embolism were found in any case.

摘要

由于多种病理生理因素,多发伤患者发生血栓栓塞并发症的风险增加。本研究的目的是分析持续静脉注射肝素预防(10000国际单位/24小时)对多发伤患者的影响。对1984年至1985年期间治疗的373例多发伤患者中的72例死亡患者进行了尸检评估。在1例患者中发现多处严重肺栓塞是其死亡原因。在任何病例中均未发现深静脉血栓形成以及暴发性肺栓塞。

相似文献

1
[Risk of lung embolism following preventive intravenous use of heparin in polytraumatized patients].[多发伤患者预防性静脉使用肝素后发生肺栓塞的风险]
Langenbecks Arch Chir. 1988;373(4):214-6. doi: 10.1007/BF01261811.
2
Low-dose subcutaneous heparin in the prevention of deep-vein thrombosis and pulmonary emboli following acute stroke.小剂量皮下注射肝素预防急性中风后深静脉血栓形成和肺栓塞
Age Ageing. 1986 Mar;15(2):84-8. doi: 10.1093/ageing/15.2.84.
3
[Prevention of venous thromboembolism in polytraumatized patients. Epidemiology and importance].[多发创伤患者静脉血栓栓塞的预防。流行病学及重要性]
Presse Med. 2000 Jan 22;29(2):68-75.
4
Heparin therapy, deep-vein thrombosis and pulmonary embolism after intracerebral hemorrhage.
Klin Wochenschr. 1988 Dec 1;66(23):1182-3. doi: 10.1007/BF01727666.
5
Heparin prophylaxis for deep vein thrombosis and pulmonary embolism.肝素预防深静脉血栓形成和肺栓塞。
West J Med. 1976 Sep;125(3):187-90.
6
Thrombo-embolism as a complication of prosthetic replacement operations of the hip: prophylaxis with heparin at low doses.
Ital J Orthop Traumatol. 1980 Apr;6(1):147-51.
7
Ultra-low dose intravenous heparin in the prevention of postoperative deep-vein thrombosis.超低剂量静脉注射肝素预防术后深静脉血栓形成
Lancet. 1980 Apr 26;1(8174):891-4. doi: 10.1016/s0140-6736(80)90834-x.
8
A comparative study of dextran-70, warfarin and low-dose heparin for the prophylaxis of thrombo-embolism following total hip replacement.右旋糖酐70、华法林和低剂量肝素预防全髋关节置换术后血栓栓塞的比较研究。
Postgrad Med J. 1977 Mar;53(617):130-3. doi: 10.1136/pgmj.53.617.130.
9
[Heparin in low dosage as prophylaxis of postoperative pulmonary embolism and deep venous thrombosis].[低剂量肝素预防术后肺栓塞和深静脉血栓形成]
Ugeskr Laeger. 1978 May 22;140(21):1224-30.
10
Prophylaxis of thromboembolism in orthopaedics and traumatology.骨科与创伤学中血栓栓塞的预防
Ann Chir Gynaecol. 1991;80(4):363-7.

本文引用的文献

1
[Special problems of thrombosis prophylaxis in trauma surgery].[创伤外科血栓预防的特殊问题]
Med Welt. 1981 Jul 31;32(30-31):1188-94.
2
[Pathophysiology of hemodynamic and metabolic disturbances following circulatory shock (author's transl)].循环性休克后血流动力学和代谢紊乱的病理生理学(作者译)
Unfallchirurgie. 1981;7(2):105-11. doi: 10.1007/BF02589640.
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Unfallheilkunde. 1982 Mar;85(3):111-5.
4
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Microthrombosis in injured and burned patients.受伤和烧伤患者的微血栓形成。
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6
[Significance of disseminated intravascular coagulation in terminal pulmonary circulation for postoperative and post-traumatic respiratory insufficiency].
Chirurg. 1974 Mar;45(3):115-20.
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[Classification of the severity of injury].[损伤严重程度的分类]
Unfallchirurg. 1985 Nov;88(11):465-72.
8
[Freshly frozen preserved plasma for the treatment of intravascular coagulation in polytraumatized patients].[新鲜冰冻保存血浆用于治疗多发伤患者的血管内凝血]
Schweiz Med Wochenschr. 1976 May 15;106(20):671-6.
9
Blood coagulation and shock.血液凝固与休克。
Pathol Res Pract. 1979 Nov;165(3):221-52. doi: 10.1016/s0344-0338(79)80073-4.
10
Recent advances in the understanding of contact activation reactions.接触激活反应认识方面的最新进展。
Semin Thromb Hemost. 1979 Spring;5(4):254-73. doi: 10.1055/s-0028-1087158.