Oberascher G
Hals-Nasen-Ohren-Abteilung der Landeskrankenanstalten Salzburg.
Laryngol Rhinol Otol (Stuttg). 1988 Aug;67(8):375-81.
The three following cerebrospinal fluid (CSF) examinations make it possible to identify even the smallest amounts of CSF in case of CSF otorrhoea and rhinorrhoea. 1. Immunological identification of beta 2-transferrin (Oberascher/Arrer) 2. Laboratory fluorescein identification (Oberascher/Arrer) 3. Endoscopic fluorescein detection according to Messerklinger. For screening, and as the method of choice, beta 2-transferrin identification is always used as a first step if there is a suspicion of liquorrhoea. Depending on the result and on further measures, both fluorescein tests are used additionally in diagnosis. Basing on practical experience gained recently, special attention is given to test analysis, the various possibilities of taking samples, and their means of transport or mailing. A newly developed diagnostic step-by-step plan is intended to emphasise the clinical significance by means of practical examples. This concept represents the present state of the art in CSF diagnosis and demonstrates that a much mor precise range of indication is possible in surgery of fractures of the base of the skull and CSF leaks if it is combined with an appropriate x-ray examination.
以下三种脑脊液(CSF)检查方法能够在脑脊液耳漏和鼻漏的情况下,即使是检测出极少量的脑脊液。1.β2-转铁蛋白的免疫学鉴定(奥伯拉舍尔/阿雷尔法)2.实验室荧光素鉴定(奥伯拉舍尔/阿雷尔法)3.根据梅塞尔克林格法进行的内镜荧光素检测。对于筛查而言,作为首选方法,如果怀疑有脑脊液漏,β2-转铁蛋白鉴定始终作为第一步使用。根据结果和进一步的检查措施,两种荧光素检测也会在诊断中额外使用。基于最近获得的实践经验,特别关注检测分析、采集样本的各种可能性及其运输或邮寄方式。一个新制定的诊断分步计划旨在通过实际案例强调其临床意义。这一概念代表了脑脊液诊断的当前技术水平,并表明如果与适当的X线检查相结合,在颅底骨折和脑脊液漏的手术中可以实现更精确的适应证范围。