From the Division of Nuclear Medicine, Medical Imaging, Centre Hospitalier de l'Université de Montréal (CHUM).
Division of Pediatric Hematology/Oncology, Montreal Children's Hospital, McGill University Health Center.
Clin Nucl Med. 2020 May;45(5):368-369. doi: 10.1097/RLU.0000000000002973.
Hemangioendotheliomas are a heterogeneous group of vascular neoplasm that may affect the liver, bone, and soft tissues. Among its variants, pseudomyogenic hemangioendothelioma is rarely encountered. Pseudomyogenic hemangioendothelioma is usually characterized by multiple soft tissue lesions, with occasional bone lesions. Fewer than 20 cases with exclusive involvement of bone structures have been reported. We describe a case of pseudomyogenic hemangioendothelioma involving multiple bony structures but without soft tissue involvement in a 7-year-old girl, imaged with F-FDG PET/CT at diagnosis and during treatment with mammalian target of rapamycin inhibitors.
血管内皮细胞瘤是一组异质性的血管肿瘤，可能影响肝脏、骨骼和软组织。在其变体中，假肌源性血管内皮细胞瘤很少见。假肌源性血管内皮细胞瘤通常表现为多发性软组织病变，偶尔伴有骨病变。仅有 20 例以下的病例报告为单纯累及骨结构。我们描述了一例 7 岁女孩的假肌源性血管内皮细胞瘤累及多个骨结构，但无软组织受累，在诊断时和使用哺乳动物雷帕霉素靶蛋白抑制剂治疗期间进行了 F-FDG PET/CT 成像。
