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骨闪烁显像和PET/CT检查显示的下肢假性肌源性血管内皮瘤

Lower-Extremity Pseudomyogenic Hemangioendothelioma on Bone Scintigraphy and PET/CT.

作者信息

Krebs Simone, Monti Serena, Lewis Natasha, Luciano Alessandro, Rastrelli Lapo, Mannelli Lorenzo

机构信息

From the *Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY; †IRCCS SDN, Naples, Italy; ‡Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY; §Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT; and ∥Carson GrahamSecondary School, North Vancouver, British Columbia, Canada.

出版信息

Clin Nucl Med. 2017 May;42(5):383-385. doi: 10.1097/RLU.0000000000001625.

DOI:10.1097/RLU.0000000000001625
PMID:28288045
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5380598/
Abstract

An otherwise healthy 33-year-old man presents with new pain involving the right leg. Radiographs of the femur showed scattered lucent lesions. An MRI of the knee demonstrated nonspecific cortical-based lesions. Biopsy confirmed pseudomyogenic hemangioendothelioma. MDP bone scan and F-FDG PET/CT were obtained to evaluate for extent of disease demonstrating disease limited to the bone of the right leg. Interestingly, the FDG and MDP uptake and CT appearance of the disease were not entirely concordant, with some lesions being lytic on CT and associated with FDG and MDP uptake, other lesions being CT silent and either MDP or FDG avid.

摘要

一名33岁原本健康的男性出现右腿新的疼痛。股骨X线片显示散在的透亮区。膝关节MRI显示非特异性皮质病变。活检确诊为假肌源性血管内皮瘤。进行了MDP骨扫描和F-FDG PET/CT以评估疾病范围,结果显示疾病局限于右腿骨骼。有趣的是,该疾病的FDG和MDP摄取及CT表现并不完全一致,一些病变在CT上呈溶骨性且伴有FDG和MDP摄取,其他病变在CT上无表现,但对MDP或FDG摄取。

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Indian J Pathol Microbiol. 2016 Jul-Sep;59(3):382-5. doi: 10.4103/0377-4929.188144.
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Pseudomyogenic hemangioendothelioma secondary to fibrous dysplasia of the left lower extremity in a 14-year-old female: a case report.一名14岁女性左下肢纤维发育异常继发假肌源性血管内皮瘤:病例报告
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Am J Surg Pathol. 2016 May;40(5):587-98. doi: 10.1097/PAS.0000000000000613.
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Cytotoxic and targeted therapy for treatment of pseudomyogenic hemangioendothelioma.用于治疗假性肌源性血管内皮瘤的细胞毒性和靶向治疗。
Clin Sarcoma Res. 2015 Oct 19;5:22. doi: 10.1186/s13569-015-0037-8. eCollection 2015.
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