Center for Injury Science, University of Alabama at Birmingham, Birmingham, Alabama.
Division of Trauma, Critical Care, and Acute Care Surgery at University of Arizona College of Medicine, Phoenix, Arizona.
Shock. 2020 Aug;54(2):205-208. doi: 10.1097/SHK.0000000000001497.
Prior research has reported an association among trauma patients between blood type O and adverse events. More recently, another study reported that severely injured trauma patients of mostly O Rh positive blood type were more likely to die.
The objective of the current study is to examine whether the same increased association is observed for blood type O severely injured patients in a more generalizable population comprised of Rh positive and Rh negative individuals.
Patients admitted to a Level-I academic trauma center between 2015 and 2018 with severe injury (Injury Severity Score >15) were included in this retrospective cohort study. Logistic regression estimated odds ratios (ORs) and 95% confidence intervals (CIs) for the association between blood type and mortality.
Among 3,913 patients, a majority were either blood type O (47.5%) or A (34.7%) and 60% were Rh positive. There was no observed difference in complication rates by blood type, and there was no observed significant association with death overall or by cause of death. There were weak, increased associations for blood type B (OR 1.61, 95% CI 0.74-3.53) and type O (OR 1.57, 95% CI 0.90-2.76) compared with blood type A patients.
Contrary to prior research, the current results suggest no association between blood type and mortality among severely injured trauma patients.
先前的研究报告称，创伤患者的血型 O 与不良事件之间存在关联。最近的另一项研究报告称，大多数 O 型 Rh 阳性血型的严重创伤患者更有可能死亡。
本研究的目的是检验在更具代表性的 Rh 阳性和 Rh 阴性个体人群中，严重受伤的 O 型血患者是否存在同样的关联。
这项回顾性队列研究纳入了 2015 年至 2018 年期间入住一级学术创伤中心的严重受伤（损伤严重程度评分>15）患者。逻辑回归估计了血型与死亡率之间的关联的比值比（OR）和 95%置信区间（CI）。
在 3913 名患者中，大多数患者的血型为 O 型（47.5%）或 A 型（34.7%），60%为 Rh 阳性。不同血型的并发症发生率没有差异，且与总死亡率或死因死亡率均无显著关联。与 A 型血患者相比，B 型血（OR 1.61，95%CI 0.74-3.53）和 O 型血（OR 1.57，95%CI 0.90-2.76）的关联稍强，呈增加趋势。
与先前的研究结果相反，目前的结果表明，严重创伤患者的血型与死亡率之间无关联。
