在FCVA系统中调节类金刚石碳（DLC）薄膜的C-C sp2/sp3比例以用于生物医学应用。

Tuning C-C sp2/sp3 ratio of DLC films in FCVA system for biomedical application.

作者信息

Rao Xi, Yang Jihan, Chen Zilin, Yuan Yidie, Chen Qiubing, Feng Xue, Qin Lizhao, Zhang Yongping

机构信息

Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, School of Materials and Energy, Southwest University, Chongqing, 400715, PR China.

Chongqing Key Laboratory of Soft-Matter Material Chemistry and Function Manufacturing, Southwest University, Chongqing, 400715, PR China.

出版信息

Bioact Mater. 2020 Feb 20;5(2):192-200. doi: 10.1016/j.bioactmat.2020.02.009. eCollection 2020 Jun.

DOI:10.1016/j.bioactmat.2020.02.009

PMID:32110741

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7033527/

Abstract

Diamond like carbon (DLC) films with different C-C sp2/sp3 ratios were prepared by tuning the N2 flow rate in a filtered cathodic vacuum arc (FCVA) system. The increase of N2 flow rate facilitated the increase of C-C sp2/sp3 ratio (1.09-2.66), the growth of particle size (0.78-1.58 nm) and the improvement of surface roughness. The SBF immersion results, as well as WCAs (77.57°~71.71°), hemolysis rate (0.14-1.00%) and cytotoxicity level (0) demonstrated that the as-fabricated DLC film was promising for biomedical application. As a result of surface charge effect, the apatite layers formed in the SBF increased with the increase of C-C sp2/sp3 ratio until 1.74 and then showed a tiny decrease during 1.74-2.66. A raise of hemolysis and cytotoxicity was observed when sp2/sp3 ratio was increased. Moreover, a decrease of friction coefficient of Si surface induced by increasing sp2/sp3 ratio was respectively evidenced in ambient air and SBF lubrication environments.

摘要

通过在过滤阴极真空电弧（FCVA）系统中调节氮气流量，制备了具有不同C-C sp2/sp3比率的类金刚石碳（DLC）薄膜。氮气流量的增加促进了C-C sp2/sp3比率的增加（从1.09到2.66）、粒径的增大（从0.78纳米到1.58纳米）以及表面粗糙度的改善。模拟体液（SBF）浸泡结果以及水接触角（77.57°至71.71°）、溶血率（0.14%至1.00%）和细胞毒性水平（0）表明，所制备的DLC薄膜在生物医学应用方面具有潜力。由于表面电荷效应，在SBF中形成的磷灰石层随着C-C sp2/sp3比率的增加而增加，直至1.74，然后在1.74至2.66之间略有下降。当sp2/sp3比率增加时，观察到溶血和细胞毒性增加。此外，在环境空气和SBF润滑环境中，分别证明了sp2/sp3比率的增加会导致硅表面摩擦系数降低。