Ewins Karl, Ní Ainle Fionnuala
Department of Haematology Rotunda Hospital and Mater Misericordiae University Hospital Dublin Ireland.
Irish Network for Venous Thromboembolism Research (INViTE) Dublin 4 Ireland.
Res Pract Thromb Haemost. 2019 Dec 26;4(2):183-192. doi: 10.1002/rth2.12290. eCollection 2020 Feb.
A State of the Art lecture, "VTE Risk Assessment in Pregnancy," was presented at the ISTH congress in Melbourne, Australia, in 2019. Venous thromboembolism (VTE) remains a leading cause of death in pregnancy and in the postpartum period. Moreover, VTE can result in lifelong disability. The elevated baseline pregnancy-associated VTE risk is further increased by additional maternal, pregnancy, and delivery characteristics, highlighting the importance of VTE risk assessment in early pregnancy, at delivery, and if risk factors change. This review will provide an overview of the impact and epidemiology of VTE in pregnancy (including reported risk factors for pregnancy-associated VTE), will address VTE risk-reduction strategies (including ongoing studies), and will provide a summary of critical knowledge gaps. Finally, throughout this review, relevant new data presented during the 2019 ISTH annual congress in Melbourne will be summarized.
2019年，一场题为“孕期静脉血栓栓塞风险评估”的前沿讲座在澳大利亚墨尔本举行的国际血栓与止血学会（ISTH）大会上发表。静脉血栓栓塞（VTE）仍然是孕期和产后死亡的主要原因。此外，VTE可导致终身残疾。与妊娠相关的VTE基线风险升高会因其他母体、妊娠和分娩特征而进一步增加，这凸显了在孕早期、分娩时以及风险因素发生变化时进行VTE风险评估的重要性。本综述将概述VTE在孕期的影响和流行病学（包括报道的与妊娠相关的VTE风险因素），探讨VTE风险降低策略（包括正在进行的研究），并总结关键的知识空白。最后，在本综述中，将总结2019年在墨尔本举行的ISTH年度大会期间展示的相关新数据。
