• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Extensive-disease small cell lung cancer, multiple relapses, five lines of therapy and more than 10-year survival.广泛期小细胞肺癌,多次复发,接受五线治疗且生存超过10年。
BMJ Case Rep. 2020 Feb 28;13(2):e232607. doi: 10.1136/bcr-2019-232607.
2
High pretreatment neutrophil-lymphocyte ratio predicts recurrence and poor prognosis for combined small cell lung cancer.治疗前高中性粒细胞与淋巴细胞比值预示着小细胞肺癌合并症的复发及不良预后。
Clin Transl Oncol. 2015 Oct;17(10):772-8. doi: 10.1007/s12094-015-1289-8. Epub 2015 Aug 5.
3
Small cell lung cancer.小细胞肺癌。
J Natl Compr Canc Netw. 2013 Jan 1;11(1):78-98. doi: 10.6004/jnccn.2013.0011.
4
Omitting elective nodal irradiation during thoracic irradiation in limited-stage small cell lung cancer--evidence from a phase II trial.局限期小细胞肺癌胸部放疗时省略选择性淋巴结照射:来自 II 期试验的证据。
Lung Cancer. 2012 Apr;76(1):72-7. doi: 10.1016/j.lungcan.2011.09.015. Epub 2011 Oct 19.
5
[Advances in study on the therapy for limited-stage small cell lung cancer].[局限期小细胞肺癌治疗研究进展]
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2013 Aug;38(8):857-62. doi: 10.3969/j.issn.1672-7347.2013.08.017.
6
Small-cell Lung Cancer in Very Elderly (≥ 80 Years) Patients.非常高龄(≥80 岁)患者的小细胞肺癌。
Clin Lung Cancer. 2019 Jul;20(4):313-321. doi: 10.1016/j.cllc.2019.05.007. Epub 2019 May 11.
7
Clinical outcome of small cell lung cancer with pericardial effusion but without distant metastasis.伴心包积液而无远处转移的小细胞肺癌的临床转归。
J Thorac Oncol. 2011 Apr;6(4):796-800. doi: 10.1097/JTO.0b013e318208ec77.
8
Treatment of extensive-stage small cell lung carcinoma: current status and future prospects.广泛期小细胞肺癌的治疗:现状与展望。
Eur Respir J. 2010 Jan;35(1):202-15. doi: 10.1183/09031936.00105009.
9
Small-cell lung cancer: a review of clinical trials.小细胞肺癌:临床试验综述
Semin Thorac Cardiovasc Surg. 2003 Oct;15(4):448-56. doi: 10.1053/s1043-0679(03)00098-4.
10
Feasibility of omitting clinical target volume for limited-disease small cell lung cancer treated with chemotherapy and intensity-modulated radiotherapy.对于接受化疗和调强放疗的局限性小细胞肺癌,省略临床靶区的可行性。
Radiat Oncol. 2014 Jan 10;9:17. doi: 10.1186/1748-717X-9-17.

引用本文的文献

1
Long-term survival in extensive-stage small-cell lung cancer treated with different immune checkpoint inhibitors in multiple-line therapies: A case report and literature review.广泛期小细胞肺癌患者接受多种免疫检查点抑制剂治疗后的长期生存:一例报告及文献复习。
Front Immunol. 2022 Nov 30;13:1059331. doi: 10.3389/fimmu.2022.1059331. eCollection 2022.

本文引用的文献

1
Best Practices Recommendations for Diagnostic Immunohistochemistry in Lung Cancer.肺癌诊断免疫组织化学的最佳实践推荐。
J Thorac Oncol. 2019 Mar;14(3):377-407. doi: 10.1016/j.jtho.2018.12.005. Epub 2018 Dec 18.
2
NCCN Guidelines Insights: Small Cell Lung Cancer, Version 2.2018.NCCN 指南解读:小细胞肺癌,2018 年版 2.0
J Natl Compr Canc Netw. 2018 Oct;16(10):1171-1182. doi: 10.6004/jnccn.2018.0079.
3
Somatostatin receptor 2 signaling promotes growth and tumor survival in small-cell lung cancer.生长抑素受体 2 信号促进小细胞肺癌的生长和肿瘤存活。
Int J Cancer. 2019 Mar 1;144(5):1104-1114. doi: 10.1002/ijc.31771. Epub 2018 Oct 9.
4
Incidence of Second Malignancy after Successful Treatment of Limited-Stage Small-Cell Lung Cancer and Its Effects on Survival.局限期小细胞肺癌治疗后第二恶性肿瘤的发生率及其对生存的影响。
J Thorac Oncol. 2017 Nov;12(11):1696-1703. doi: 10.1016/j.jtho.2017.07.030. Epub 2017 Aug 10.
5
RECIST 1.1-Update and clarification: From the RECIST committee.RECIST 1.1更新与说明:来自RECIST委员会。
Eur J Cancer. 2016 Jul;62:132-7. doi: 10.1016/j.ejca.2016.03.081. Epub 2016 May 14.
6
Somatostatin receptor expression in small cell lung cancer as a prognostic marker and a target for peptide receptor radionuclide therapy.生长抑素受体在小细胞肺癌中的表达作为一种预后标志物及肽受体放射性核素治疗的靶点
Oncotarget. 2016 Apr 12;7(15):20033-40. doi: 10.18632/oncotarget.7706.
7
Long-Term Survival of a Patient With Non-Small-Cell Lung Cancer Harboring a V600E Mutation in the BRAF Oncogene.一名携带BRAF癌基因V600E突变的非小细胞肺癌患者的长期生存情况
Clin Lung Cancer. 2016 Mar;17(2):e17-21. doi: 10.1016/j.cllc.2015.12.001. Epub 2015 Dec 18.
8
The 2015 World Health Organization Classification of Lung Tumors: Impact of Genetic, Clinical and Radiologic Advances Since the 2004 Classification.2015 年世界卫生组织肺肿瘤分类:自 2004 年分类以来遗传、临床和放射学进展的影响。
J Thorac Oncol. 2015 Sep;10(9):1243-1260. doi: 10.1097/JTO.0000000000000630.
9
10-year long-term survival of a metastatic EGFR-mutated nonsmall cell lung cancer patient.一名转移性表皮生长因子受体(EGFR)突变的非小细胞肺癌患者的10年长期生存情况
Eur Respir J. 2015 Jul;46(1):280-2. doi: 10.1183/09031936.00017315. Epub 2015 Apr 16.
10
Long-term survival of non-small-cell lung cancer patients with EGFR inhibitor treatment.表皮生长因子受体(EGFR)抑制剂治疗非小细胞肺癌患者的长期生存情况。
Genet Mol Res. 2014 Oct 27;13(4):8657-60. doi: 10.4238/2014.October.27.5.

广泛期小细胞肺癌,多次复发,接受五线治疗且生存超过10年。

Extensive-disease small cell lung cancer, multiple relapses, five lines of therapy and more than 10-year survival.

作者信息

Singh Pawan Kumar, Shrestha Deepa Kumari, Singh Navneet, Gupta Nalini

机构信息

Department of Pulmonary Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India

Department of Pulmonary Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

BMJ Case Rep. 2020 Feb 28;13(2):e232607. doi: 10.1136/bcr-2019-232607.

DOI:10.1136/bcr-2019-232607
PMID:32111707
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7050376/
Abstract

Small cell lung cancer (SCLC) accounts for nearly 18% of lung cancer cases. Most of the patients of SCLC are not surgical candidates, due to advanced stage at presentation hence only viable options are chemotherapy and radiotherapy. Long-term survival in SCLC is extremely rare due to relapses and comorbidities. Ten-year survival has never been reported in cases with extensive disease at presentation and history of relapses. Here we are describing a case of extensive disease SCLC who has survived multiple relapses and has received five lines of systemic therapy apart from radiation and palliative care. This case emphasises on the need of active and strict disease surveillance at each follow-up.

摘要

小细胞肺癌(SCLC)占肺癌病例的近18%。大多数小细胞肺癌患者不适合手术,因为就诊时已处于晚期,因此唯一可行的选择是化疗和放疗。由于复发和合并症,小细胞肺癌的长期生存极为罕见。对于就诊时为广泛期疾病且有复发史的患者,从未有过十年生存的报道。在此,我们描述一例广泛期小细胞肺癌患者,该患者多次复发后存活,除放疗和姑息治疗外还接受了五线全身治疗。该病例强调了每次随访时积极、严格的疾病监测的必要性。