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根治性膀胱切除术术后加速康复方案的内部审计

Internal audit of an enhanced recovery after surgery protocol for radical cystectomy.

作者信息

Ghodoussipour Saum, Naser-Tavakolian Aurash, Cameron Brian, Mitra Anirban P, Miranda Gus, Cai Jie, Bhanvadia Sumeet, Aron Monish, Desai Mihir, Gill Inderbir, Schuckman Anne, Daneshmand Siamak, Djaladat Hooman

机构信息

USC Institute of Urology, USC/Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, USA.

出版信息

World J Urol. 2020 Dec;38(12):3131-3137. doi: 10.1007/s00345-020-03135-w. Epub 2020 Feb 28.

Abstract

PURPOSE

To perform an internal audit 5 years after implementation of our enhanced recovery after surgery (ERAS) protocol for patients undergoing radical cystectomy and to investigate the importance of physician driven compliance on outcomes.

METHODS

Using a prospectively maintained database, 472 consecutive patients were identified who underwent radical cystectomy with ERAS from July 2013 to July 2017. Compliance was measured by a Composite Compliance Score (CCS) generated as a percentage of 16 interventions. Patients with higher than median compliance were compared to patients with lower compliance. The primary outcome was length of stay. Secondary outcomes included complication and readmission rates. Multivariable regressions were used to control for differences between groups.

RESULTS

In 2013, median CCS was 81% and subsequently ranged from 81 to 88%. Five-year median CCS was 88%. Patients with higher compliance (CCS ≥ 88%, n = 262), as compared to those with lower compliance (CCS < 88%, n = 210), were younger (median 70.3 vs 72.7 years, p = 0.047), healthier (ASA3-4 81% vs 89.9%, p = 0.007), received more orthotopic diversions (59.2% vs 37.6%, p < 0.0001), more often had open surgery (78.5% vs 51.9%, p < 0.0001) and had shorter median operative times (5.5 vs 6.3 h, p = 0.005). Median length of stay was 4 days. Higher compliance was associated with shorter hospital stays (β = - 0.85, 95% CI - 1.62 to - 0.07) and decreased 30-day readmissions (OR 0.58, 95% CI 0.35-0.96).

CONCLUSIONS

Greater ERAS compliance was achieved in younger and healthier patients. Patients with greater compliance had a decreased length of stay by almost 1 day and reduced odds of 30-day readmissions.

摘要

目的

在我们针对接受根治性膀胱切除术的患者实施强化术后康复(ERAS)方案5年后进行内部审计,并调查医生主导的依从性对治疗结果的重要性。

方法

使用前瞻性维护的数据库,确定了2013年7月至2017年7月期间连续472例行ERAS根治性膀胱切除术的患者。依从性通过综合依从性评分(CCS)来衡量,该评分以16项干预措施的百分比表示。将依从性高于中位数的患者与依从性较低的患者进行比较。主要结局是住院时间。次要结局包括并发症和再入院率。使用多变量回归来控制组间差异。

结果

2013年,CCS中位数为81%,随后在81%至88%之间。五年CCS中位数为88%。与依从性较低的患者(CCS<88%,n=210)相比,依从性较高的患者(CCS≥88%,n=262)更年轻(中位数70.3岁对72.7岁,p=0.047),更健康(ASA3-4级分别为81%对89.9%,p=0.007),接受原位改道的比例更高(59.2%对37.6%,p<0.0001),更常接受开放手术(78.5%对51.9%),p<0.0001)且中位手术时间更短(5.5小时对6.3小时,p=0.005)。中位住院时间为4天。更高的依从性与更短的住院时间相关(β=-0.85,95%CI-1.62至-0.07),并降低了30天再入院率(OR 0.58,95%CI 0.35-0.96)。

结论

年轻和健康的患者对ERAS的依从性更高。依从性更高的患者住院时间缩短了近1天,30天再入院几率降低。

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