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伴有脊椎骨髓炎时是否会改变有症状的颈前路颈椎硬膜外脓肿患者的手术治疗?一项机构分析。

Should the Presence of Spondylodiscitis Alter the Surgical Treatment of Patients with Symptomatic Ventral Cervical Epidural Abscesses? An Institutional Analysiss.

机构信息

The Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

The Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

出版信息

World Neurosurg. 2020 Jun;138:e282-e288. doi: 10.1016/j.wneu.2020.02.103. Epub 2020 Feb 26.

Abstract

BACKGROUND

Spinal epidural abscess is a rare pathology with an incidence that has tripled in the past 2 decades. Ventral cervical epidural abscesses (vCEA) of the cervical spine pose particular treatment challenges because of the anatomical location. The aim of this report is to identify trends in the surgical management of these patients and to determine whether concomitant spondylodiscitis warrants fusion at the index surgery.

METHODS

Patients presenting to a quaternary care institution from January 2009 to December 2018 with isolated vCEA were identified. Patients were excluded if they had dorsal or circumferential epidural abscesses. Clinical and radiographic data were collected. Patients with vCEA were stratified by the presence or absence of spondylodiscitis upon presentation. Clinical outcomes analyzed included neurological sequelae and the need for revision surgery.

RESULTS

During the 10-year study period, 36 patients presented with symptomatic isolated vCEA and constituted the study cohort; 16 (44%) had concurrent spondylodiscitis. All 36 patients underwent surgical decompression; the initial surgical approach was anterior-only for 7 patients (19%), posterior-only for 27 patients (75%), and and a combined approach for 2 patients (6%). Four patients from the total cohort (11%) ultimately required a revision operation; all 4 were from the subset with concurrent spondylodiscitis (25% vs. 0%, P = 0.03).

CONCLUSIONS

vCEA can be evacuated safely and effectively by a variety of strategies in patients with neurologic deficits. Concomitant spondylodiscitis with cervical epidural abscess may warrant instrumented fusion as part of the initial surgical strategy.

摘要

背景

脊髓硬膜外脓肿是一种罕见的疾病,在过去 20 年中其发病率增加了两倍。颈椎腹侧硬膜外脓肿(vCEA)由于解剖位置特殊,治疗极具挑战性。本报告旨在确定此类患者手术治疗的趋势,并确定是否同时存在脊椎炎需要在初次手术时融合。

方法

从 2009 年 1 月至 2018 年 12 月,在一家四级医疗机构就诊的患有孤立性 vCEA 的患者被确定。如果患者存在背侧或环状硬膜外脓肿,则将其排除在外。收集了临床和影像学数据。根据就诊时是否存在脊椎炎,将患有 vCEA 的患者分为两组。分析了临床结果,包括神经后遗症和需要进行翻修手术的情况。

结果

在 10 年的研究期间,36 名患有症状性孤立性 vCEA 的患者构成了研究队列,其中 16 名(44%)同时患有脊椎炎。所有 36 名患者均接受了手术减压;最初的手术方法是仅前路 7 例(19%),仅后路 27 例(75%),前后联合入路 2 例(6%)。总队列中有 4 名患者(11%)最终需要进行翻修手术;这 4 名患者均来自同时患有脊椎炎的亚组(25%比 0%,P=0.03)。

结论

对于有神经功能缺损的患者,通过多种策略可以安全有效地排空 vCEA。颈椎硬膜外脓肿并发脊椎炎可能需要在初始手术策略中进行器械融合。

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