School of Public Health, University of Montreal, Montreal, QC, Canada; Centre de recherche de l'IUSMM, Montreal, QC, Canada; CRCHUS, CIUSSS de l'Estrie-CHUS, Sherbrooke, QC, Canada.
CRCHUS, CIUSSS de l'Estrie-CHUS, Sherbrooke, QC, Canada.
Value Health. 2020 Feb;23(2):251-259. doi: 10.1016/j.jval.2019.08.008. Epub 2019 Oct 3.
Population norms for the EQ-5D-5L were published in Canada but only for Alberta province. The purpose of this study was to derive Quebec population norms from the EQ-5D-5L.
The data came from a larger study conducted between September 2016 and March 2018 using elicitation techniques for a quality-adjusted life-year project. The online survey was distributed randomly in the province of Quebec. To best describe the entire population, data were stratified by various sociodemographic characteristics such as age, gender, urban and rural populations, whether disadvantaged or not, immigrant or nonimmigrant, and health problems.
A total of 2704 (53.8%) respondents completed the EQ-5D-5L. Mean (95% confidence interval) and median (interquartile range) utility scores were 0.824 (0.818-0.829) and 0.867 (0.802-0.911), respectively. The EQ-VAS scores were estimated at 75.9 (75.2-76.6) and 80 (69-90). Subjects with lower scores were those who had a low or high body mass index; were smokers; were single, divorced, or widowed; had no children; were unemployed or sick; had lower education or lower annual income; and had a family or personal history of serious illness. Immigrants had higher scores. There was no difference in gender and urban or rural population. The score logically decreased with worsening health status, from a mean score of 0.896 (0.884-0.908) to 0.443 (0.384-0.501; P < .0001. Similar results were observed for subjects' satisfaction with their health or life. Subjects with lower scores were less willing to take risks. Subjects who declared they were affected by health problems presented significant lower utility scores, ranging from 0.554 (nervous problem) to 0.750 (cancer), compared with those without health problems (0.871; confidence interval: 0.867-0.876).
This is the first study to present utility score norms for EQ-5D-5L for the Quebec population. These results will be useful for comparison with quality-adjusted life-year studies to better interpret their results. Moreover, utility norms were provided for 21 health problems, which was rarely done.
加拿大曾公布 EQ-5D-5L 的人群常模，但仅限于艾伯塔省。本研究旨在从 EQ-5D-5L 中得出魁北克省的人群常模。
数据来自于 2016 年 9 月至 2018 年 3 月间进行的一项较大规模的研究，该研究使用了质量调整生命年项目的 elicitation 技术。该在线调查在魁北克省随机分发。为了最好地描述整个人群，根据年龄、性别、城乡人口、是否处于不利地位、移民或非移民以及健康问题等各种社会人口特征对数据进行分层。
共有 2704 名（53.8%）受访者完成了 EQ-5D-5L 问卷。效用评分的平均值（95%置信区间）和中位数（四分位间距）分别为 0.824（0.818-0.829）和 0.867（0.802-0.911），EQ-VAS 评分估计为 75.9（75.2-76.6）和 80（69-90）。得分较低的人群包括：身体质量指数较低或较高的人群、吸烟者、单身、离异或丧偶的人群、没有子女的人群、失业或患病的人群、受教育程度较低或年收入较低的人群、以及有家庭或个人严重疾病史的人群。移民的得分较高。性别、城乡人口差异无统计学意义。随着健康状况的恶化，得分呈逻辑下降，从平均 0.896（0.884-0.908）降至 0.443（0.384-0.501；P<0.0001）。对于受调查者对健康或生活的满意度也观察到了类似的结果。得分较低的受调查者不太愿意冒险。与没有健康问题的人群（0.871；置信区间：0.867-0.876）相比，报告有健康问题的人群效用评分显著较低，范围为 0.554（神经问题）至 0.750（癌症）。
这是第一项针对魁北克人群的 EQ-5D-5L 效用评分常模的研究。这些结果将有助于与质量调整生命年研究进行比较，以更好地解释其结果。此外，还为 21 种健康问题提供了效用常模，这很少见。
