School of Public Health, Nanjing Medical University, 101 Longmian Avenue, Jiangning District, Nanjing, 211166, China.
Section of School Health, Changzhou Municipal Center for Disease Control and Prevention, Changzhou, 213022, China.
Health Qual Life Outcomes. 2024 Nov 28;22(1):102. doi: 10.1186/s12955-024-02322-2.
This study aims to establish EQ-5D-Y-3L population norms in Jiangsu, China by conducting a large-scale cross-sectional survey.
Children and adolescents aged 9-17 from three cities of Jiangsu Province were selected by multistage stratified random sampling to complete the EQ-5D-Y-3L instrument independently. Population norms for Jiangsu, China were determined by calculating statistics based on age and gender. Logistic and Tobit regression models were employed to explain the relationship between HRQoL and factors such as sociodemographic characteristics/recent acute symptoms (experienced fever/cough/sore throat/diarrhea in the past two weeks).
Three cities yielded 37,574 valid samples (a sample validity rate of 95.4%). The EQ-5D-Y-3L utility values (mean ± SD) were 0.964 ± 0.085 for males and 0.958 ± 0.077 for females. Males scored 85.94 ± 19.62 and females scored 84.83 ± 18.45 on the VAS (mean ± SD), while the percentages of respondents reporting full health ranged from 58.3 to 78.8%. The dimension in which most respondents reported having no problems was "feeling worried, sad, or unhappy" (23.0%). And the lowest HRQoL was shown in the 14-year-old age group. Gender, age, board at school, and BMI were found to have an association with HRQoL. In addition, recent acute symptoms also correlate with some aspects of HRQoL.
This study established EQ-5D-Y-3L population norms in Jiangsu, China for the first time. These norms will support resource allocation decision-making and be used as a reference for health evaluation studies.
本研究旨在通过大规模横断面调查，建立中国江苏省 EQ-5D-Y-3L 人群规范。
采用多阶段分层随机抽样方法，选取江苏省三个城市 9-17 岁儿童青少年，独立完成 EQ-5D-Y-3L 量表。根据年龄和性别计算统计量，确定中国江苏省人群规范。采用 logistic 和 Tobit 回归模型解释 HRQoL 与社会人口学特征/近期急性症状（过去两周内发热/咳嗽/咽痛/腹泻）等因素的关系。
三个城市共获得 37574 例有效样本（样本有效率 95.4%）。EQ-5D-Y-3L 效用值（均值±标准差）男性为 0.964±0.085，女性为 0.958±0.077。男性 VAS 评分为 85.94±19.62，女性为 84.83±18.45，自述完全健康的比例为 58.3%-78.8%。报告无问题的维度最多的是“感觉忧虑、悲伤或不开心”（23.0%）。HRQoL 最低的是 14 岁年龄组。性别、年龄、学校类型和 BMI 与 HRQoL 有关。此外，近期急性症状也与 HRQoL 的某些方面相关。
本研究首次建立了中国江苏省 EQ-5D-Y-3L 人群规范。这些规范将支持资源配置决策，并作为健康评估研究的参考。
