Green Lane Cardiovascular Service, Auckland City Hospital, Auckland, New Zealand; Department of Cardiology, Middlemore Hospital, Auckland, New Zealand.
Green Lane Cardiovascular Service, Auckland City Hospital, Auckland, New Zealand; Department of Cardiology, Middlemore Hospital, Auckland, New Zealand.
Heart Lung Circ. 2020 Aug;29(8):1210-1216. doi: 10.1016/j.hlc.2020.01.008. Epub 2020 Feb 17.
Type A aortic dissection is a fatal condition warranting emergency surgery to prevent complications and death. We reviewed the contemporary trends, characteristics, outcomes and predictors of this operation at our centre over a 14-year period.
Consecutive patients undergoing type A aortic dissection surgery at Auckland City Hospital during March 2003-March 2017 were studied, and relevant characteristics and outcomes collected prospectively for statistical analyses.
There were 327 patients included, and the number of operations each year remained similar from 2003-2010, and steadily increased thereafter. Median age was 60.6 years, with 124 (37.9%) females, 136 (41.6%) Maori or Pacific ethnicity, 319 (97.6%) emergency surgeries, 62 (19.0%) in a critical preoperative state and 154 (47.1%) having a malperfusion syndrome. Operative mortality occurred in 65 (19.9%), although this has decreased from 23.3% before 2014 to 14.0% since. Composite morbidity occurred in 212 (65.0%), predominantly acute kidney injury 134 (41.0%), ventilation >24 hours (129 (39.6%), return to theatre 94 (28.8%) and stroke 63 (19.3%). Survival at 1, 5 and 10 years was 79.0%, 71.7% and 57.8% respectively. Critical preoperative state and malperfusion syndrome were independent predictors of operative and long-term mortality and composite morbidity.
Surgery for acute type A aortic dissection has been increasing since 2011 and continues to have high rates of operative mortality and morbidities, although the former has decreased since 2014. Critical preoperative state and malperfusion were the key predictors of adverse outcomes. After surviving the perioperative period, prognosis was good with low rates of late mortality.
A型主动脉夹层是一种致命的疾病,需要紧急手术以预防并发症和死亡。我们回顾了我们中心在过去 14 年中进行的这种手术的当代趋势、特征、结果和预测因素。
对 2003 年 3 月至 2017 年 3 月期间在奥克兰市医院接受 A 型主动脉夹层手术的连续患者进行了研究,并前瞻性地收集了相关特征和结果进行统计分析。
共纳入 327 例患者,2003 年至 2010 年每年手术例数保持相似,此后稳步增加。中位年龄为 60.6 岁,124 例(37.9%)为女性,136 例(41.6%)为毛利人或太平洋岛民,319 例(97.6%)为急诊手术,62 例(19.0%)处于术前危急状态,154 例(47.1%)存在灌注不良综合征。65 例(19.9%)发生手术死亡率,尽管自 2014 年以来已从 23.3%下降。212 例(65.0%)发生复合发病率,主要为急性肾损伤 134 例(41.0%),通气时间>24 小时 129 例(39.6%),重返手术室 94 例(28.8%)和中风 63 例(19.3%)。1、5 和 10 年的生存率分别为 79.0%、71.7%和 57.8%。术前危急状态和灌注不良综合征是手术和长期死亡率及复合发病率的独立预测因素。
自 2011 年以来,急性 A 型主动脉夹层手术一直在增加,手术死亡率和发病率仍然很高,尽管自 2014 年以来有所下降。术前危急状态和灌注不良是不良预后的关键预测因素。在度过围手术期后,预后良好,晚期死亡率较低。