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膝关节前交叉韧带重建术后感染:单中心数据库 1891 例患者的队列研究。

Knee infection following anterior cruciate ligament reconstruction: a cohort study of one thousand, eight hundred and ninety one patients from the single-centre database.

机构信息

St.Catherine Specialty Hospital, Bračak 8, Zabok, Croatia.

Department for Orthopaedic Surgery, University Hospital, "Sveti Duh," Sveti Duh 64, Zagreb, Croatia.

出版信息

Int Orthop. 2020 May;44(5):869-875. doi: 10.1007/s00264-020-04500-5. Epub 2020 Feb 29.

Abstract

PURPOSE

This study was undertaken to retrospectively determine the incidence of postoperative knee infection following ACL reconstruction, to identify the most common causative pathogen and to evaluate our diagnostic and treatment approach, as well as to review current recommendations for the management of septic arthritis.

METHODS

From January 2007 to December 2017, a total of 1891 arthroscopic ACL reconstructions were performed at our institution. Twenty-nine cases with clinical suspicion of post-operative septic knee arthritis following ACL reconstruction were identified and retrospectively analysed with regard to incidence, clinical presentation, microbiological spectrum, laboratory parameters and number of arthroscopic debridements. Three patients were classified as aseptic effusion and were excluded from the further analysis. Patients were treated with antibiotic therapy (IV and oral) and repeated arthroscopic debridement.

RESULTS

Twenty-six (1.4%) out of 1891 patients were diagnosed with joint infection and were treated with arthroscopic debridement and intravenous antibiotics. In the majority of cases (58.69%), microbiological analysis failed to identify the causative pathogen and in those where the pathogen was isolated, the most common was methicillin-resistant Staphylococcus epidermidis (45.45%). Mean time interval from reconstruction to onset of symptoms was 23.54 ± 21.00 (6-100) days. The mean number of arthroscopic irrigations and debridements was 1.23 ± 0.51 (1-3) per patient. In all, twenty-six cases of graft was retained.

CONCLUSION

Septic arthritis following ACL reconstruction is a rare but serious complication. We conclude that prompt treatment consisting of repeated arthroscopic irrigation and debridement with course of antibiotic therapy is an effective therapeutic intervention that leads to graft and hardware retention.

摘要

目的

本研究旨在回顾性确定 ACL 重建术后膝关节感染的发生率,确定最常见的病原体,并评估我们的诊断和治疗方法,以及回顾目前对化脓性关节炎管理的建议。

方法

从 2007 年 1 月至 2017 年 12 月,我院共进行了 1891 例关节镜下 ACL 重建术。共发现 29 例临床怀疑 ACL 重建术后膝关节感染的病例,并对其临床表现、微生物谱、实验室参数和关节镜清创次数进行回顾性分析。3 例患者被归类为无菌性积液,因此被排除在进一步分析之外。患者接受抗生素治疗(静脉和口服)和重复关节镜清创。

结果

在 1891 例患者中,有 26 例(1.4%)诊断为关节感染,并采用关节镜清创和静脉内抗生素治疗。在大多数情况下(58.69%),微生物分析未能确定病原体,而在病原体分离的情况下,最常见的病原体是耐甲氧西林表皮葡萄球菌(45.45%)。从重建到症状出现的平均时间间隔为 23.54±21.00(6-100)天。每位患者平均进行 1.23±0.51 次关节镜冲洗和清创。所有病例均保留了移植物。

结论

ACL 重建术后的化脓性关节炎是一种罕见但严重的并发症。我们的结论是,及时进行多次关节镜冲洗和清创,并辅以抗生素治疗,是一种有效的治疗干预措施,可保留移植物和内固定物。

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