Rudolph Almut, Hilbert Anja
Clinical Psychology and Psychotherapy, Department of Psychology, Faculty of Life Sciences, University of Leipzig, Leipzig, Germany.
Integrated Research and Treatment Center Adiposity Diseases, Departments of Medical Psychology and Medical Sociology and Psychosomatic Medicine and Psychotherapy, Leipzig University Medical Center, Leipzig, Germany.
Front Psychiatry. 2020 Feb 12;11:14. doi: 10.3389/fpsyt.2020.00014. eCollection 2020.
Binge-eating disorder (BED) and major depressive disorder (MDD) following bariatric surgery are significant predictors for less post-operative weight loss and/or weight regain, however, cognitive-behavioral therapy (CBT) addressing these disorders following surgery has not been investigated so far.
This study examined feasibility of a short-term CBT based on evidence-based manuals for BED and MDD that were adapted to patients following bariatric surgery, and investigated its effectiveness in improving weight loss outcome, psychopathology, and psychosocial functioning.
In an uncontrolled proof-of-concept study, the CBT manual was piloted in N = 7 patients who had undergone roux-en-Y gastric bypass surgery at least 6 months before. Weight loss, eating disorder psychopathology, depressive symptoms, and self-esteem were assessed using clinical interviews and self-report questionnaires at pre-treatment, post-treatment, and in a 3-month follow-up.
A significant reduction of body weight was found as well as medium to large effects in the improvement of eating disorder psychopathology, depressive symptoms, and self-esteem from pre-treatment to post-treatment were found. Most of those changes remained stable during the 3-month follow-up period. Study retention was 71.4%.
Feasibility and effectiveness of CBT were documented for patients with BED or MDD following bariatric surgery. Adaptations of the study procedure for proof-of-efficacy in randomized-controlled studies are discussed.
减肥手术后出现的暴饮暴食症(BED)和重度抑郁症(MDD)是术后体重减轻较少和/或体重反弹的重要预测因素,然而,目前尚未对术后针对这些疾病的认知行为疗法(CBT)进行研究。
本研究检验了基于循证手册针对减肥手术后患者改编的用于治疗BED和MDD的短期CBT的可行性,并调查了其在改善体重减轻结果、精神病理学和心理社会功能方面的有效性。
在一项非对照的概念验证研究中,对7名至少在6个月前接受过胃旁路手术的患者试用了CBT手册。在治疗前、治疗后和3个月随访时使用临床访谈和自我报告问卷评估体重减轻、饮食失调精神病理学、抑郁症状和自尊。
发现体重显著减轻,并且从治疗前到治疗后,饮食失调精神病理学、抑郁症状和自尊的改善有中等至较大效果。这些变化大多在3个月随访期内保持稳定。研究保留率为71.4%。
记录了减肥手术后患有BED或MDD患者CBT的可行性和有效性。讨论了在随机对照研究中为证明疗效而对研究程序进行的调整。