Hashishin Takahiro, Osawa Taisei, Miyamoto Kazunori, Uchiyama Masanobu
Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.
Research Initiative for Supra-Materials (RISM), Shinshu University, Ueda, Japan.
Front Chem. 2020 Feb 4;8:12. doi: 10.3389/fchem.2020.00012. eCollection 2020.
Stannylation of calcium carbide followed by Sn-hypervalent iodine(III) exchange reaction cleanly afforded the electrophilic ethynylating agent ethynyl(phenyl)-λ-iodane in high yield. This two-step method uses very inexpensive materials and is readily operable without any special precautions.
碳化钙经甲锡烷基化，随后进行高价碘（III）交换反应，以高产率顺利制得亲电乙炔化试剂乙炔基（苯基）-λ-碘烷。此两步法使用非常廉价的原料，且无需任何特殊防护措施即可轻松操作。
