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吸食大麻对口腔健康的影响:快速证据综述

Oral Health Implications of Cannabis Smoking: A Rapid Evidence Review.

作者信息

Keboa Mark Tambe, Enriquez Ninoska, Martel Marc, Nicolau Belinda, Macdonald Mary Ellen

出版信息

J Can Dent Assoc. 2020 Jan;86:k2.

Abstract

OBJECTIVES

To summarize evidence relating cannabis smoking and oral disease and highlight any potential influence of cannabis smoking on clinical care and dental public health.

METHODS

Using rapid evidence review, a librarian facilitated a systematic search of 5 electronic databases in August and September 2018 and updated it in March 2019, yielding 581 publications. Two researchers screened the documents using pre-established inclusion criteria: article was based on primary or secondary data; cannabis smoking was an exposure; at least 1 cannabis-related oral health outcome was reported; participants were humans; and the article was available in English or French. Data from retained articles were analyzed for themes without meta-analysis.

RESULTS

We synthesized and summarized 23 articles in 2 broad categories: cannabis and oral disease; and cannabis, clinical care and dental public health. Current evidence shows that smoking cannabis is harmful to the health of the periodontium. The association between smoking cannabis and other oral disease (dental caries, soft tissue lesions and oral cancers) is sparse and inconsistent, although studies suggest that cannabis smoking is an underlying risk factor. Cannabis smoking can lead to an altered mental state that can delay dental treatment of the patient. Further, interactions between smoked cannabis and adrenaline-containing local anesthetics can result in life-threatening consequences.

CONCLUSIONS

Cannabis smoking is harmful to the periodontium. Further research is needed to fully understand how cannabis smoking affects oral disease and how dental professionals should integrate this knowledge into clinical care and dental public health.

摘要

目的

总结与吸食大麻和口腔疾病相关的证据,并强调吸食大麻对临床护理和牙科公共卫生的任何潜在影响。

方法

通过快速证据回顾,一名图书馆员于2018年8月和9月对5个电子数据库进行了系统检索,并于2019年3月进行了更新,共检索到581篇出版物。两名研究人员使用预先确定的纳入标准对文献进行筛选:文章基于原始或二手数据;吸食大麻为暴露因素;至少报告了1项与大麻相关的口腔健康结果;参与者为人类;文章以英文或法文提供。对保留文章的数据进行主题分析,未进行荟萃分析。

结果

我们综合并总结了23篇文章,分为两大类:大麻与口腔疾病;大麻、临床护理和牙科公共卫生。目前的证据表明,吸食大麻对牙周健康有害。吸食大麻与其他口腔疾病(龋齿、软组织病变和口腔癌)之间的关联较少且不一致,尽管研究表明吸食大麻是一个潜在风险因素。吸食大麻会导致精神状态改变,从而延误患者的牙科治疗。此外,吸食的大麻与含肾上腺素的局部麻醉剂之间的相互作用可能会导致危及生命的后果。

结论

吸食大麻对牙周有害。需要进一步研究以充分了解吸食大麻如何影响口腔疾病,以及牙科专业人员应如何将这些知识纳入临床护理和牙科公共卫生。

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